🏷️ Parameter	🔍 Details
🧬 Active Ingredient	Venlafaxine (Extended-Release)
💊 Indication	Major Depressive Disorder, Generalized Anxiety, Panic Disorder, Social Anxiety
🇺🇸 US Brand	Effexor XR®
🏭 Manufacturer	Cipla Ltd.
📦 Packaging	Strips of 10 capsules
💪 Strength	37.5 mg, 75 mg, 150 mg
🚚 Delivery Time	7–14 days (Worldwide)

🧠 Introduction to Venlor XR

Venlor XR by Cipla contains Venlafaxine, a serotonin-norepinephrine reuptake inhibitor (SNRI) in extended-release capsules. Key features:

⏳ Once-daily dosing: Maintains stable plasma concentrations
📈 Dual mechanism: Inhibits reuptake of serotonin (low dose) and norepinephrine (≥75mg)
⚠️ Black-box warning: Increased suicidality in young adults
❗ High discontinuation syndrome risk (avoid abrupt stoppage)

Cipla’s 10-capsule strips ensure accurate dosing for conditions like treatment-resistant depression and generalized anxiety disorder (GAD).

💊 Dosage & Indications

💉 Indication	🧪 Dosage	⏱️ Frequency	💡 Notes
Major Depression	Start 75mg → Max 225mg/day	Once daily	Take with food
Generalized Anxiety	37.5-150mg/day	Once daily	Morning dose
Panic Disorder	Start 37.5mg → 75-225mg/day	Once daily	Titrate weekly
Renal/Hepatic Impairment	Reduce dose by 50%	–	Avoid in severe cases

⚠️ Side Effects, Storage & Warnings

❗ Common Side Effects:
- Nausea (35%)
- Headache (25%)
- Insomnia (18%)
- Hypertension (12% at >150mg/day)
🚫 Serious Risks:
- Suicidal ideation (age <24)
- Serotonin syndrome
- Angle-closure glaucoma
❄️ Storage: 15-30°C; protect from moisture (keep in original strip).
⚠️ Critical Warnings:
- Monitor BP weekly for first 3 months
- Taper gradually (reduce by 75mg/week)
- Contraindicated with MAOIs (14-day washout)

🌍 Global Availability & Shipping

🌎 Region	📦 Shipping	💵 Price (10-capsule strip)	📜 Prescription
🇺🇸 USA	✅ Yes	$20–$40	Required
🇬🇧 UK	✅ Yes	£15–£30	Required
🇦🇺 Australia	✅ Yes	AUD 25–45	Required

🔗 Related Indian Alternatives (Different in Same Category)

💊 Product Name	🏭 Manufacturer	🔗 Internal Link
Etilaam (Etizolam)	Intas	etilaam
Nexito (Escitalopram)	Sun Pharma	nexito
Zosert (Sertraline)	Sun Pharma	zosert
Prodep (Fluoxetine)	Sun Pharma	prodep
Mirtaz (Mirtazapine)	Intas	mirtaz
Dulane (Duloxetine)	Cipla	dulane

📚 External Medical References

🩺 Expert Commentary

Dr. Sameer Verma, Psychiatrist:
“Venlor XR’s dual SNRI action makes it effective for depression with fatigue, but monitor BP diligently at doses >150mg. For elderly patients, [nexito] (Escitalopram) has fewer interactions. Cipla’s capsules have ‘CIPLA’ printed on them – never crush or chew.”

📌 Disclaimer

This information is not medical advice. Use under physician supervision. Cipla’s Venlor XR carries black-box warnings for suicidality.

💡 Clinical Protocol:

Dosing Strategy:

Condition Starting Dose Therapeutic Range Titration

Depression 75mg 150-225mg +75mg/week

GAD 37.5mg 75-150mg +37.5mg/week
Discontinuation Syndrome Management:

Symptom Action

Dizziness Reduce by 37.5mg every 4 days

“Brain zaps” Short-term benzodiazepine bridge

Severe symptoms Reinstate dose + slower taper
Capsule Identification:
- 37.5mg: Yellow cap/body
- 75mg: Orange cap/body
- 150mg: Burnt orange cap/body
Drug Interactions:

Concomitant Drug Risk Action

SSRIs/TCAs ↑ Serotonin syndrome risk Avoid

NSAIDs ↑ Bleeding risk Monitor for bruising

Warfarin ↑ INR Frequent INR checks
Hypertension Monitoring:
- Baseline BP → Weekly ×1 month → Monthly thereafter
- Discontinue if BP >140/90 mmHg unresponsive to antihypertensives