Name: Abhigra 100mg
Brand: HAB Pharma
SKU: Abhigra
Availability: InStock

💊 Abhigra 100mg — pharmaceutical-grade sildenafil citrate by HAB Pharma. Generic alternative to Viagra®.

📦 Product Specifications

💊 Generic NameSildenafil Citrate

🏷️ Brand NameAbhigra

💪 Dosage Strength100 mg per tablet

📦 Packaging10 tablets per strip

🏭 ManufacturerHAB Pharma

📋 Drug ClassPDE5 Inhibitor

⏱️ Onset of Action30–60 minutes (empty stomach)

🏭

Manufactured by HAB Pharma
HAB Pharma is a trusted pharmaceutical company known for producing high-quality generic medications. Abhigra 100mg contains Sildenafil Citrate, the same active ingredient as Viagra®, and is manufactured under strict quality standards. It is a PDE5 inhibitor that helps increase blood flow to the penis, enabling an erection in response to sexual stimulation.

🔬 How Abhigra (Sildenafil) Works

⚙️ Mechanism of Action

Sildenafil selectively inhibits phosphodiesterase type 5 (PDE5), the enzyme responsible for breaking down cGMP in the corpus cavernosum. When sexual stimulation causes local release of nitric oxide (NO), PDE5 inhibition leads to increased cGMP levels, resulting in smooth muscle relaxation and enhanced blood inflow to the penis. This allows men with erectile dysfunction to achieve and maintain an erection sufficient for sexual activity.

📊 Pharmacokinetics

Bioavailability: ~40%
Peak plasma: 30–120 minutes (fasting)
Food effect: High-fat meal delays absorption by ~1 hour, reduces peak levels
Protein binding: 96%
Half-life: ~4 hours
Metabolism: Liver (CYP3A4, CYP2C9)
Excretion: 80% feces, 13% urine

💊 Dosage & Administration

Standard Dosing

Starting dose: 50 mg as needed, ~1 hour before sexual activity
Dose range: 25–100 mg based on effectiveness and toleration
Maximum dose: 100 mg per day
Frequency: Maximum once per day
Timing window: 30 minutes to 4 hours before sexual activity

Special Populations – Start with 25 mg

Elderly (≥65 years)
Hepatic impairment (e.g., cirrhosis)
Severe renal impairment (CrCl <30 mL/min)
Concomitant strong CYP3A4 inhibitors
Ritonavir: Max 25 mg in 48 hours

⚠️ Important: Sexual stimulation is required for Abhigra to work – it does not cause an automatic erection. Take on an empty stomach for fastest absorption; a high-fat meal may delay onset.

⚠️

CRITICAL CONTRAINDICATIONS & WARNINGS

DO NOT TAKE ABHIGRA IF:

You take any nitrates (nitroglycerin, isosorbide mononitrate/dinitrate) – even recreationally (“poppers” like amyl nitrate). Combining can cause a sudden, dangerous drop in blood pressure leading to heart attack or stroke.
You take guanylate cyclase stimulators (riociguat for pulmonary hypertension).
You are allergic to sildenafil or any tablet ingredients.
Sexual activity is inadvisable due to cardiovascular status.

❤️

Cardiovascular Considerations

Sildenafil has mild vasodilatory properties, causing transient decreases in blood pressure (mean 8.4/5.5 mmHg). Use with caution in patients with:

Left ventricular outflow obstruction (aortic stenosis, IHSS)
Severely impaired autonomic control of blood pressure
Myocardial infarction, stroke, or life-threatening arrhythmia within the last 6 months
Resting hypotension (BP <90/50 mmHg) or hypertension (BP >170/110 mmHg)
Cardiac failure or coronary artery disease causing unstable angina

Consult your doctor if you have any cardiovascular conditions before using Abhigra.

📋 Side Effects & Precautions

Common Side Effects (≥2%)

Headache (10-16%)
Flushing (10%)
Dyspepsia / indigestion (7%)
Nasal congestion (4%)
Dizziness (2%)
Nausea (2%)
Visual disturbances (3%) – blue/green color tinge, light sensitivity

Serious Adverse Events (Seek Immediate Medical Attention)

Prolonged erection >4 hours (priapism) – can cause permanent tissue damage
Sudden vision loss in one or both eyes (NAION)
Sudden hearing decrease or loss
Severe hypotension (especially with nitrates)
Chest pain, shortness of breath – seek emergency care

🔄 Important Drug Interactions

Drug Class / Examples	Interaction	Recommendation
Nitrates (nitroglycerin, isosorbide, amyl nitrate)	Severe hypotension	CONTRAINDICATED
Alpha-blockers (doxazosin, tamsulosin)	Additive hypotensive effects	Initiate sildenafil at 25 mg
CYP3A4 inhibitors (ketoconazole, erythromycin)	↑ sildenafil exposure (3-fold)	Consider starting dose 25 mg
Ritonavir (HIV protease inhibitor)	↑↑ sildenafil exposure (11-fold)	Max 25 mg in 48 hours
Rifampin (CYP3A4 inducer)	↓ sildenafil levels	Monitor efficacy

📚 Authoritative References

⚠️ Important Medical Information

Sildenafil is a prescription medication used for erectile dysfunction. It should not be taken by individuals taking nitrates (for chest pain) or riociguat. This product is intended for use by men over 18 years of age. Consult your healthcare provider before use, especially if you have heart disease, high or low blood pressure, liver or kidney disease, a history of stroke, or conditions predisposing to priapism. Do not exceed the recommended dose of one tablet per day. Seek immediate medical attention if you experience an erection lasting longer than 4 hours, sudden vision loss, or sudden hearing loss. This information is for educational purposes only and does not replace professional medical advice. Keep out of reach of children.

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