Aciloc 300mg

🌟 Quick Reference Table

🌍 Introduction: Aciloc 300mg in Gastrointestinal Care

Aciloc 300mg, manufactured by Cadila Pharmaceuticals, is an H2-receptor antagonist containing ranitidine, traditionally used to reduce stomach acid in conditions like GERD, peptic ulcers, and heartburn. Following global recalls of ranitidine due to NDMA (a probable carcinogen) contamination, Cadila ensures compliance with updated safety standards. This guide covers its uses, global availability, and current safety protocols.

⚠️ Important Safety Note

• Recall Status: Ranitidine products were withdrawn in the US/EU in 2020. In India, some batches remain available under revised guidelines.

• Alternatives: PPIs (e.g., Pantoprazole) or other H2 blockers (e.g., Famotidine) are often recommended.

🔬 Chemical Composition & Mechanism

• Active Ingredient: Ranitidine hydrochloride (300mg).

• Excipients: Microcrystalline cellulose, magnesium stearate.

• Mechanism: Blocks histamine H2 receptors in stomach parietal cells, reducing acid secretion by 70–80%.

🌐 Global Availability & Pricing

United States

• Status: Discontinued (Zantac® recalled).

• Alternatives: Famotidine (Pepcid®).

India

• Brands: Aciloc (Cadila), Rantac (J.B. Chemicals).

• OTC Status: Prescription-only post-recall.

• Price: ₹50–₹150 per strip (30 tablets).

United Kingdom

• Status: Withdrawn from market (2020).

• Alternatives: Cimetidine, Famotidine.

Australia

• TGA Status: Suspended.

📊 Price Comparison (Per 30-Tablet Strip)

🏭 Manufacturer Spotlight: Cadila Pharmaceuticals

• Founded: 1951 in Ahmedabad, India.

• Reputation: Leading producer of gastrointestinal and cardiovascular drugs.

• Certifications: WHO-GMP, USFDA-approved facilities.

• Innovation: Focus on affordable generics post-patent expiries.

💊 Dosage & Administration

✅ Adults:

• GERD/Ulcers: 150–300mg once or twice daily.

• Zollinger-Ellison: Up to 600mg daily.

⚠️ Contraindications:

• Hypersensitivity to ranitidine, porphyria.

• Avoid with rilpivirine (HIV medication).

📦 Storage:

• 🌡️ Store below 25°C in a dry place.

• 🔒 Protect from light and moisture.

⚠️ Side Effects & Precautions

🩺 Expert Review: Dr. Arjun Desai, MD (Gastroenterology)

*“While Aciloc 300mg was once a frontline therapy, post-recall, its use is limited. Cadila’s current batches comply with stricter NDMA limits, but alternatives like PPIs are safer for long-term use.”*

🔗 Internal Links to Indian GI Medications

1. Pantop-DSR: Pantoprazole + Domperidone for acid reflux.

2. Rablet 20mg: Rabeprazole for GERD.

3. Famocid 40mg: Famotidine H2 blocker.

📜 Trusted References

• FDA Ranitidine Recall

• WHO NDMA Guidelines

• NHS Heartburn Advice

❓ FAQs

Q: Is Aciloc 300mg safe post-recall?
A: Cadila claims compliance with NDMA limits, but consult a doctor for alternatives.

Q: Can I buy Aciloc in the US?
A: No—ranitidine is discontinued; consider famotidine or PPIs.

Q: Is Aciloc safe during pregnancy?
A: Category B—use only if benefits outweigh risks.