โ Active Ingredient Overview Table:
| ๐ฌ Active Ingredient (Generic Name): | Benzoyl Peroxide |
|---|---|
| ๐ Indication: | Acne Vulgaris (Comedonal & Inflammatory Lesions) |
| ๐บ๐ธ US Brand Equivalent: | Clearasil, PanOxyl |
| ๐ญ Manufacturer: | Wallace Pharmaceuticals Pvt. Ltd. (Founded: 1977) |
| ๐ฆ Packaging: | 30 g Tube |
| ๐งช Strength: | 5% w/w |
| ๐ Delivery Time: | 6โ15 days |
๐ฟ What is Benzoyl Peroxide 5% Gel (Persol AC)?
Persol AC 5% Gel delivers benzoyl peroxide, a cornerstone in acne therapy with both antibacterial and keratolytic properties. Benzoyl peroxide penetrates follicles, releasing oxygen that eradicates Propionibacterium acnes, a key acne-causing bacterium. Simultaneously, it exfoliates follicular epithelium, preventing comedone formation and reducing inflammation.
Patients with mild to moderate acne often struggle with persistent papules, pustules, and blackheads, leading to scarring and diminished self-esteem. Persol ACโs non-prescription gel base ensures easy application and rapid skin penetration. Within weeks of nightly use, most patients observe fewer lesions and smoother skin texture.
๐งฌ Pharmacology & Mechanism of Action
| Attribute | Detail |
|---|---|
| Chemical Formula | C14H10O4 |
| Molecular Weight | 242.23 g/mol |
| Mode of Action | Releases free radicals โ oxidizes bacterial proteins; keratolytic by softening and shedding stratum corneum cells |
| Antibacterial Spectrum | Effective against P. acnes and some anaerobic bacteria |
๐ก Indications & Application Guidelines
| Condition | Application |
|---|---|
| Acne Vulgaris | โข Cleanse and dry affected areas. |
| โข Apply a thin layer of Persol AC Gel once or twice daily to acne lesions. | |
| โข Begin with once-nightly use; increase to twice daily as tolerated. | |
| โข Continue for at least 6โ8 weeks to assess efficacy. |
Avoid contact with eyes, lips, and mucous membranes. Use non-comedogenic moisturizer to mitigate dryness. If irritation occurs, reduce frequency.
โ ๏ธ Warnings & Side Effects
Common:
- Dryness, peeling, mild erythema
- Transient stinging or burning sensation
Less Common:
- Contact dermatitis
- Hypersensitivity reactions (rash, swelling)
Precautions:
- Conduct patch test if sensitive skin.
- Use sunscreen daily; photosensitivity may increase.
- Avoid contact with dyed fabrics; may bleach hair and textiles.
Discontinue if severe irritation develops. Consult a dermatologist for persistent eczema or dermatitis.
๐ฅ Storage Instructions
Store Persol AC Gel at 20โ25ยฐC in its original tube. Protect from light and moisture. Ensure cap is tightly closed between uses. Keep out of reach of children.
๐ Availability & Purchasing
- United States: Over-the-counter benzoyl peroxide gels (2.5%โ10%) available; healthcare providers may recommend 5% strength.
- United Kingdom & EU: Available OTC in various strengths; Persol AC can be imported with a valid prescription.
- Australia: OTC benzoyl peroxide products accessible; 5% formulations may require pharmacist guidance.
Persol AC 5% Gel from India offers cost-effective acne management. Adhere to local import regulations and maintain prescription documentation.
๐ Authoritative Resources
๐ Topical Therapies (Indian Brands)
- Clindac A Gel โ Clindamycin Phosphate 1% gel for inflammatory acne.
- Adapen Gel โ Adapalene 0.1% gel for comedonal lesions and long-term maintenance.
- Aziderm 10% Gel โ Azelaic Acid 10% gel for acne and rosacea.
๐ฅ Educational Video on Acne Management
๐จโโ๏ธ Expert Insight: Dr. Anjali Mehta, Dermatologist
โBenzoyl peroxide remains a first-line topical therapy for acne due to its rapid antibacterial action and comedolytic properties. Persol ACโs 5% formulation balances efficacy with tolerability, making it suitable for a broad patient population.โ




