Betnovate C

Betamethasone/Clioquinol

Price range: $15.00 through $35.00

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Betnovate C
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โœ… Active Ingredient Overview Table:

๐Ÿ”ฌ Active Ingredients: Betamethasone Valerate 0.1% w/w, Clioquinol 3% w/w
๐Ÿ’Š Indication: Infected Dermatoses, Eczematous Dermatitis with Secondary Bacterial/Fungal Infection
๐Ÿ‡บ๐Ÿ‡ธ US Brand Equivalent: N/A (Comparable components: Diprolene for Betamethasone, Vioform for Clioquinol)
๐Ÿญ Manufacturer: GlaxoSmithKline Pharmaceuticals Ltd (Founded: 2000)
๐Ÿ“ฆ Packaging: 30 g Tube
๐Ÿงช Strengths: Betamethasone Valerate 0.1% w/wClioquinol 3% w/w
๐Ÿšš Delivery Time: 6โ€“15 days

๐ŸŒฟ What Is Betnovate C Ointment?

Betnovate C combines a potent topical corticosteroid (Betamethasone Valerate 0.1%) with Clioquinol 3%, an antibacterial and antifungal agent. This combination is indicated for inflammatory dermatoses complicated by secondary bacterial or fungal infection, such as impetiginized eczema, intertrigo, and infected psoriasis. Betamethasone reduces inflammation, itching, and erythema, while Clioquinol targets superficial Gram-positive bacteria (e.g., Staphylococcus aureus) and dermatophytes, hastening resolution of infection and preventing spread.


๐Ÿงฌ Pharmacology & Mechanism of Action

Component Mechanism
Betamethasone Valerate 0.1% โ€ข Binds glucocorticoid receptors โ†’ downregulates pro-inflammatory cytokines (ILโ€‘1, TNFโ€‘ฮฑ) โ€ข Inhibits leukocyte infiltration and histamine release โ†’ reduces pruritus and erythema
Clioquinol 3% โ€ข Chelates metal ions in bacterial/fungal enzymes โ†’ disrupts membrane permeability, impairing DNA synthesis โ€ข Effective against Gramโ€‘positive cocci and dermatophytes
Ointment Base โ€ข Provides occlusion โ†’ enhances skin penetration of actives and maintains moist environment for healing

๐Ÿ’ก Indications & Application Guidelines

Condition Application Regimen
Impetiginized Eczema / Intertrigo with Infection โ€ข Gently cleanse and pat dry the affected area. โ€ข Apply a thin layer of Betnovate C Ointment 1โ€“2 times daily until infection resolves (usually 7โ€“10 days). โ€ข Discontinue Clioquinol component after 7 days; continue Betamethasone monoโ€‘therapy if inflammation persists (max 14 days total).
Infected Psoriatic Lesions โ€ข Cleanse area; apply Betnovate C to plaques with surrounding erythema twice daily. โ€ข Use for up to 7 days; switch to topical steroid alone thereafter.
Bacterial/Fungal Superinfection (e.g., Tinea, Candidal) โ€ข Cleanse and dry; apply thin layer twice daily for 7โ€“10 days. โ€ข Monitor for resolution; if fungal elements persist, consider systemic therapy or fungalโ€‘specific topical after initial control with Betnovate C.

Avoid application to face, groin, and axilla unless directed. Do not bandage or occlude unless under specialist supervision. Discontinue if severe irritation or hypersensitivity occurs.


โš ๏ธ Warnings & Side Effects

Common:

  • Local burning or stinging upon application
  • Dryness or peeling in sensitive areas
  • Mild folliculitis

Less Common:

  • Contact dermatitis (allergic)
  • Hypopigmentation or hypertrichosis with prolonged steroid use

Serious (Rare):

  • Secondary fungal overgrowth (e.g., Candida) if used beyond recommended duration
  • HPA axis suppression (with extensive or occluded use)
  • Telangiectasia or skin atrophy in treated area

Precautions:

  • Limit Betamethasone use to 14 days in body, 7 days in intertriginous areas.
  • Use Clioquinol component only for 7โ€“10 days to reduce resistance risk and mucosal irritation.
  • Avoid in children under 2 years unless under pediatric dermatologist supervision.
  • Do not apply to deep puncture wounds, animal bites, or uncleaned burn areas.

Inform patients to report signs of hypersensitivity (rash, swelling, severe itching) immediately and to use sunscreen if applied to sunโ€‘exposed areas.


๐Ÿฅ Storage Instructions

Store Betnovate C Ointment at 20โ€“25ยฐC in its original tube. Protect from direct sunlight and moisture. Replace cap securely after each use. Keep out of reach of children and pets.


๐ŸŒ Availability & Purchasing

  • United States: No direct branded Betnovate C; components available separately by prescription (e.g., Diprolene & clioquinol formulations). Combination compounding possible in specialized pharmacies under physician order.
  • United Kingdom & EU: Betnovate C prescribed by dermatologists; combination topical corticosteroid/antibiotic preparations are prescriptionโ€‘only.
  • Australia: Betnovate C available under PBS; prescription required for infected dermatoses.

Importing Betnovate C from India must comply with personal importation regulations; ensure a valid prescription and complete customs documentation to avoid delays.


๐Ÿ”— Authoritative Resources


๐Ÿ”— Related Topical Therapies (Indian Brands)


๐ŸŽฅ Educational Video on Combination Therapies for Infected Dermatitis


๐Ÿ‘ฉโ€โš•๏ธ Expert Insight: Dr. Ramesh Patel, Dermatologist

โ€œBetnovate C Ointment addresses both inflammation and secondary infection in one formulation. Its combined action shortens healing time, reduces scarring, and prevents recurrence in impetiginized eczema and other infected dermatoses.โ€


Additional Information

Active

Betamethasone/Clioquinol

Tube/s

3, 6, 12

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