✅ Active Ingredient Overview Table:
| 🔬 Active Ingredient (Generic Name): | Permethrin |
|---|---|
| 💊 Indication: | Scabies (Sarcoptes scabiei infestation) |
| 🇺🇸 US Brand: | Elimite, Nix |
| 🏭 Manufacturer: | Menarini India Pvt Ltd (Founded: 1995) |
| 📦 Packaging: | 30 g Tube |
| 🧪 Strength: | 5% w/w |
| 🚚 Delivery Time: | 6–15 days |
🌿 What is Permethrin 5% Cream (Scabper)?
Scabper Cream 5% offers a potent, single-application solution for scabies, an intensely pruritic and contagious skin infestation caused by Sarcoptes scabiei. Beyond physical discomfort—marked by relentless itching and rash—scabies inflicts psychological distress, sleep deprivation, and social stigma. Scabper’s high-potency formulation rapidly penetrates the stratum corneum to paralyze and eradicate mites and eggs in one overnight treatment.
Menarini’s Scabper is engineered with emollients that soothe inflamed skin and promote barrier repair, addressing post-scabetic dermatitis. A single 30 g tube covers the entire body surface of adults and children, facilitating household-wide treatment to break the transmission cycle. Clinical data demonstrate cure rates exceeding 95% after one application, improving both dermatologic and quality-of-life outcomes.
🧬 Pharmacology & Mechanism of Action
| Attribute | Detail |
|---|---|
| Chemical Formula | C21H20Cl2O3 |
| Molecular Weight | 391.29 g/mol |
| Mode of Action | Voltage-gated sodium channel disruption |
| Residual Activity | Up to 24 hours |
Permethrin binds to parasite sodium channels, causing continuous nerve depolarization, paralysis, and death of mites and their eggs.
💡 Indications & Application Protocol
| Condition | Application Steps |
|---|---|
| Scabies Infestation | • Apply cream from the neck down to feet, including under nails. |
| • Leave on for 8–14 hours (overnight). | |
| • Rinse off thoroughly with water. | |
| • Repeat once after 7 days if live mites or symptoms persist. |
Ensure comprehensive coverage, especially in webs of fingers, wrists, and genital areas. Launder clothing and bedding in hot water.
⚠️ Warnings & Side Effects
Common:
- Mild burning or tingling sensation
- Temporary itching and redness
Serious (rare):
- Contact dermatitis
- Neurologic signs if over-applied (avoid mucosal contact)
Avoid use on broken skin, eyes, or scalp. In infants (<2 months) and pregnant women, consult a physician before application.
🏥 Storage Instructions
Store Scabper Cream at 20–25°C in its original tube. Protect from light and moisture. Keep out of reach of children.
🌐 Availability & Purchasing
- USA: Prescription-only (Elimite); generic permethrin for lice OTC.
- UK & EU: Prescription required; permethrin scabicide available.
- Australia: TGA-approved; prescription-only.
Menarini’s Scabper is an affordable, reliable treatment. Ensure adherence to local prescribing guidelines.
🔗 Related Parasitic Treatments
- Permiforce Cream 5% – Healing Pharma permethrin.
🎥 Educational Video on Scabies Management
👨⚕️ Expert Insight: Dr. Priya Menon, Dermatologist
“Scabper Cream 5% simplifies scabies care with one overnight application. Patient education on proper application and household cleaning is critical to prevent reinfestation.”

