| 🏷️ Parameter | 🔍 Details |
|---|---|
| 🧬 Active Ingredient | Trihexyphenidyl Hydrochloride |
| 💊 Indication | Parkinsonism, Drug-Induced Extrapyramidal Symptoms (EPS), Dystonia |
| 🇺🇸 US Brand | Artane® (discontinued); generic available |
| 🏭 Manufacturer | Intas Pharmaceuticals Ltd. |
| 📦 Packaging | Blister strips of 10 tablets |
| 💪 Strength | 2 mg |
| 🚚 Delivery Time | 7–15 days (Worldwide) |
🧠 Introduction to Bexol (Trihexyphenidyl)
Bexol contains Trihexyphenidyl, a central anticholinergic agent manufactured by Intas India. It restores dopamine-acetylcholine balance in basal ganglia, providing relief for:
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🥼 Parkinson’s symptoms: Rigidity, tremors, and sialorrhea (excessive drooling)
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💊 Drug-induced EPS: Caused by antipsychotics (e.g., rigidity from Haloperidol)
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💪 Dystonia: Muscle spasms in neck/limbs (off-label)
Unlike levodopa, Bexol doesn’t cause dyskinesias but requires cautious dosing in elderly due to cognitive side effects.
💊 Dosage & Indications
| 💉 Indication | 🧪 Dosage | ⏱️ Frequency | 💡 Route |
|---|---|---|---|
| Parkinsonism (Adults) | 1–2 mg/day → Max 15 mg/day | 3–4 divided doses | Oral |
| Drug-Induced EPS (Adults) | 5–15 mg/day | Divided doses | Oral |
| Dystonia (Off-label) | 2–5 mg TID | Max 20 mg/day | Oral |
| Pediatric EPS (≥3 years) | 0.05–0.1 mg/kg/day | Divided doses | Oral |
⚠️ Side Effects, Storage & Warnings
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❗ Common Side Effects: Dry mouth, blurred vision, constipation, urinary retention.
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🚫 Serious Effects:
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Confusion/hallucinations (elderly)
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Angle-closure glaucoma (emergency)
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Tachycardia (heart rate >100 bpm)
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❄️ Storage: Below 30°C; protect from moisture (desiccant in bottle).
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⚠️ Warnings:
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Contraindicated in glaucoma, myasthenia gravis, or bowel obstruction.
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Avoid in dementia patients (↑ cognitive impairment risk).
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Discontinue gradually to prevent rebound symptoms.
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🌍 Global Availability & Shipping
| 🌎 Region | 📦 Shipping | 💵 Price (10 tablets) | 📜 Prescription |
|---|---|---|---|
| 🇺🇸 USA | ✅ Yes | $15–$25 | Required |
| 🇬🇧 UK | ✅ Yes | £12–£20 | Required |
| 🇦🇺 Australia | ✅ Yes | AUD 20–35 | Required |
🔗 Related Indian Alternatives (Different in Same Category)
| 💊 Product Name | 🏭 Manufacturer | 🔗 Internal Link |
|---|---|---|
| Pacitane (Trihexyphenidyl) | Sun Pharma | Pacitane |
| Artane (Trihexyphenidyl) | Pfizer | Artane |
| Syndopa (Levodopa-Carbidopa) | Sun Pharma | Syndopa |
| Pramipex (Pramipexole) | Intas | Pramipex |
| Ropark (Ropinirole) | Sun Pharma | Ropark |
| Benexol (Benztropine) | Alembic Pharma | Benexol |
📚 External Medical References
🩺 Expert Commentary
Dr. Vikram Patel, Neurologist:
*”Bexol remains essential for young Parkinson’s patients with tremor-predominant symptoms. For antipsychotic-induced EPS, start with 2mg BID and monitor for anticholinergic toxicity. Rotigotine patches ([Neupro]) are preferable for elderly.”*
📌 Disclaimer
This article is informational only. Consult a neurologist before use. Intas’ Bexol is not FDA-approved for dystonia.
💡 Clinical Tips:
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Acute Dystonia Rescue: 5 mg IM + posture correction (onset: 10–15 min).
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Dry Mouth Management: Sugar-free gum/pilocarpine drops.
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Switching Strategy: Replace 5 mg Bexol with 2 mg [Benexol] (less cognitive impact).

