β Active Ingredient Overview Table:
| π¬ Active Ingredients: | Clotrimazole 1% w/v, Beclometasone Dipropionate 0.05% w/v |
|---|---|
| π Indication: | Inflammatory Dermatoses with Fungal Infection |
| πΊπΈ US Brand Equivalent: | No exact combination; Clotrimazole (Lotrimin), Beclomethasone (QVAR) separately |
| π Manufacturer: | Glenmark Pharmaceuticals Ltd (Founded: 1977) |
| π¦ Packaging: | 30 ml Bottle |
| π§ͺ Strength: | Clotrimazole 1%, Beclometasone Dipropionate 0.05% |
| π Delivery Time: | 6β15 days |
πΏ What Is Candid B Lotion?
Candid B Lotion combines Clotrimazole, an imidazole antifungal agent, with Beclometasone Dipropionate, a medium-potency corticosteroid. This lotion is indicated for inflammatory skin conditionsβsuch as tinea with secondary inflammation (e.g., tinea corporis, tinea cruris)βwhere fungal infection and erythema, pruritus, and scaling coexist. Clotrimazole inhibits ergosterol synthesis in fungal cell membranes, leading to cell death, while Beclometasone Dipropionate reduces inflammation, itching, and redness by modulating inflammatory cytokines and inhibiting leukocyte migration.
𧬠Pharmacology & Mechanism of Action
| Component | Mechanism |
|---|---|
| Clotrimazole 1% | β’ Inhibits 14Ξ±-demethylase β prevents conversion of lanosterol to ergosterol β disrupts fungal cell membrane integrity β fungistatic/fungicidal |
| Beclometasone Dipropionate 0.05% | β’ Binds to glucocorticoid receptors β alters gene transcription β reduces production of inflammatory mediators (IL-1, TNF-Ξ±) β vasoconstriction reduces erythema and pruritus |
| Lotion Base | β’ Emollient aqueous/ethanol vehicle β facilitates even application, rapid absorption, and patient comfort |
π‘ Indications & Application Guidelines
| Condition | Application Regimen |
|---|---|
| Tinea Corporis / Cruris with Inflammation | β’ Cleanse and pat dry affected area. |
| β’ Apply Candid B Lotion thinly to affected and adjacent areas twice daily (morning and evening). | |
| β’ Continue for 2 weeks; reassess fungal clearance before discontinuation of Clotrimazoleβcontinue Beclometasone only if inflammation persists (max 10 days total corticosteroid use). | |
| Intertrigo / Candidal Intertrigo (Inflamed) | β’ Cleanse intertriginous folds gently; apply lotion twice daily to affected folds for 7β10 days. |
| β’ Discontinue corticosteroid after inflammation subsides; continue antifungal for additional 1β2 weeks to eradicate fungal infection. | |
| Infected Psoriatic or Eczematous Lesions with Fungal Colonization | β’ Cleanse lesion; apply lotion twice daily for 7 days. |
| β’ On resolution of infection, switch to appropriate monotherapy (antifungal or corticosteroid) as needed. |
- Preparation: Wash hands and affected site; gently dry.
- Application: Shake bottle well. Dispense a small amount onto fingertip or cotton pad; spread evenly over lesion and 1β2 cm surrounding margin.
- Frequency: Use twice daily. If irritation occurs, reduce to once daily.
- Duration: Clotrimazole component: typically 2β4 weeks. Beclometasone component: no more than 10 consecutive days to avoid skin atrophy and HPA axis suppression.
- Precautions: Avoid occlusive dressings unless directed. Do not apply to open wounds or mucous membranes. Avoid contact with eyes. In pediatric or elderly patients, monitor for signs of systemic absorption.
β οΈ Warnings & Side Effects
Common:
- Transient burning or stinging at application site
- Mild dryness or peeling
Less Common:
- Contact dermatitis (allergic) to Clotrimazole or excipients
- Skin atrophy, striae, or telangiectasia with prolonged corticosteroid use
Serious (Rare):
- Secondary fungal or bacterial superinfection if used beyond recommended duration
- HPA axis suppression with extensive or prolonged use of Beclometasone under occlusion or large surface areas
Precautions:
- Limit Beclometasone use to 10 days; discontinue if skin thinning or significant irritation occurs.
- Avoid application on face, groin, or axilla for >5 days without specialist supervision.
- If no improvement after 7 days, reevaluate diagnosis or consider culture-directed therapy.
- Discontinue if signs of severe irritation or hypersensitivity (erythema, swelling, vesiculation) develop.
π₯ Storage Instructions
Store Candid B Lotion at 20β25Β°C in its original bottle. Protect from light and moisture. Ensure cap is tightly closed after each use. Discard 6 months after opening. Keep out of reach of children.
π Availability & Purchasing
- United States: No direct combination; separate prescriptions for topical Clotrimazole and Beclometasone.
- United Kingdom & EU: Prescription required; combination topical steroid/antifungal products available under dermatologist guidance.
- Australia: Prescription necessary; combination products exist under specialist prescription.
Importing Candid B Lotion from India may reduce costs. Ensure compliance with personal importation regulations; maintain valid prescription to avoid customs delays.
πAuthoritative Resources
π Related Topical Therapies (Indian Brands)
- Fucidin H Cream β Fusidic Acid 2% / Betamethasone Valerate 0.1% for infected eczema.
π₯ Educational Video on Combination Steroid/Antifungal Therapy
Learn how Candid Bβs dual-action formulation treats inflammatory fungal dermatoses effectively:
π©ββοΈ Expert Insight: Dr. Sangeeta Patel, Dermatologist
βCandid B Lotion offers synergistic antifungal and anti-inflammatory action, making it ideal for fungal infections with pronounced inflammation. By limiting corticosteroid duration, clinicians can minimize side effects while achieving rapid symptom relief.β




