Name: Nucoxia
SKU: 8811
Availability: InStock

🔬 Active Ingredient (Generic Name):	Etoricoxib
💊 Indication:	Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis, Acute Pain
🏭 Manufacturer:	Zydus Cadila Pharma (Founded: 1952)
📦 Packaging:	10 Tablets per Strip
🧪 Strengths:	60 mg, 90 mg, 120 mg
🚚 Delivery Time:	6–15 days

🌿 What is Nucoxia (Etoricoxib)?

Nucoxia contains Etoricoxib, a selective COX-2 inhibitor. It blocks the cyclooxygenase-2 enzyme, reducing prostaglandin production in inflamed tissues while sparing COX-1 in the stomach. Consequently, it offers effective pain and inflammation control with a lower risk of gastrointestinal side effects compared to non-selective NSAIDs.

🧬 Chemical Profile & Mechanism

Attribute	Detail
Chemical Formula	C18H15ClN2O2S
Molecular Weight	358.84 g/mol
Bioavailability	~100%
Metabolism	Hepatic (CYP3A4)
Half-Life	~22 hours

By selectively inhibiting COX-2, Etoricoxib reduces inflammatory mediators while preserving gastric mucosal protection.

💡 Indications & Usage

Osteoarthritis: 60 mg once daily for pain and stiffness.
Rheumatoid Arthritis: 90 mg once daily to control joint inflammation.
Ankylosing Spondylitis: 90 mg once daily for spinal pain and stiffness.
Acute Pain: 120 mg as a single dose for short-term relief (e.g., postoperative pain).

💊 Dosage Guidelines

Strength	Recommended Dose
60 mg	Osteoarthritis: 60 mg once daily
90 mg	RA, AS: 90 mg once daily
120 mg	Acute pain: Single 120 mg dose (do not exceed one dose)

Take once daily with or without food. Swallow tablets whole with water.

⚠️ Safety & Side Effects

Common Adverse Effects:

Headache
Hypertension
Diarrhea, dyspepsia

Serious Risks:

Cardiovascular events (e.g., myocardial infarction)
Renal impairment
Serious skin reactions

Use smallest effective dose for shortest duration. Monitor blood pressure, renal function, and cardiovascular status, especially in high-risk patients.

🏥 Storage Instructions

Store Nucoxia at 20–25°C in a dry, dark place. Keep in original blister to protect from moisture. Keep out of reach of children.

🌐 Global Availability & Purchasing

United States: Available only under special import programs; prescription required.
United Kingdom & EU: Prescription-only COX-2 inhibitor.
Australia: Schedule 4; prescription required; import with TGA approval.

Import from India may reduce costs; ensure compliance with local regulations and hold a valid prescription.

🔗 Related Medications

Celecoxib 200 mg – COX-2 selective inhibitor.
Diclofenac 75 mg SR – extended-release NSAID.
Meloxicam 15 mg – preferential COX-2 inhibitor.
Naproxen 250 mg – non-selective NSAID.
Ibuprofen 400 mg – common OTC NSAID.

🎥 Educational Video on Etoricoxib

👨‍⚕️ Expert Insight: Dr. Arvind Patel, Rheumatologist

“Etoricoxib offers targeted inflammation control with reduced GI risks. However, cardiovascular monitoring is essential in long-term use, especially in patients with underlying heart disease.”