Labetalol Injection

Labetalol Injection is a fast-acting medication used to manage severe hypertension (high blood pressure) in emergency situations. It contains the active ingredient Labetalol Hydrochloride and is available in two common strengths: 4ml and 20ml. This article provides a comprehensive guide to Labetalol Injection, including its chemical composition, uses, dosages, side effects, and how to buy it in the USA, UK, Australia, and through import from India.

What is Labetalol Injection?

Labetalol Injection is a sterile solution containing Labetalol Hydrochloride, a dual-action beta-blocker that works by blocking both alpha and beta-adrenergic receptors. This helps relax blood vessels and reduce heart rate, making it effective in treating hypertensive emergencies.

Chemical Composition of Labetalol Injection

The active ingredient, Labetalol Hydrochloride, has the chemical formula C19H24N2O3·HCl. It is a white crystalline powder that is soluble in water and alcohol. The injection is typically available in concentrations of 5 mg/mL (for 4ml vials) and 25 mg/mL (for 20ml vials).

For more detailed information on the chemical structure, you can refer to the FDA’s official drug database.

Uses of Labetalol Injection

Labetalol Injection is primarily used for:

1. Hypertensive Emergencies: It is administered in hospital settings to quickly lower dangerously high blood pressure.
2. Post-Surgical Hypertension: It can be used to manage high blood pressure following surgery.
3. Pregnancy-Induced Hypertension: Labetalol Injection is considered safe for use during pregnancy to manage severe hypertension.

Dosage and Administration

The dosage of Labetalol Injection depends on the patient’s condition and response to treatment. Common dosages include:

• Initial Dose: 20 mg (4ml of 5 mg/mL solution) administered intravenously over 2 minutes.
• Maintenance Dose: 40-80 mg (8-16ml of 5 mg/mL solution) every 10 minutes, up to a maximum of 300 mg.

Always follow your healthcare provider’s instructions and never adjust the dosage without consulting a doctor.

How to Buy Labetalol Injection in the USA, UK, and Australia

Buying Labetalol Injection in the USA

In the United States, Labetalol Injection is available by prescription only. It is typically administered in hospitals or emergency settings. However, some specialty pharmacies may supply it for home use under strict medical supervision.

Buying Labetalol Injection in the UK

In the UK, Labetalol Injection is available through the NHS or private pharmacies. A prescription from a GP or specialist is required. It is primarily used in hospital settings.

Buying Labetalol Injection in Australia

In Australia, Labetalol Injection is available with a prescription from a licensed healthcare provider. It is commonly used in hospitals and emergency departments.

Importing Labetalol Injection from India

India is a leading producer of generic medications, including Labetalol Injection. Many Indian pharmaceutical companies manufacture high-quality generic versions at significantly lower prices. Some popular Indian brands include:

• Labebloc Injection (Manufactured by Sun Pharmaceutical Industries Ltd., founded in 1983)
• Labetal Injection (Manufactured by Cipla Ltd., founded in 1935)
• Lopressor Injection (Manufactured by Dr. Reddy’s Laboratories, founded in 1984)

When importing Labetalol Injection from India, ensure that the supplier is reputable and complies with international quality standards. Always check for proper licensing and certifications.

Prices of Labetalol Injection

The cost of Labetalol Injection varies depending on the country, brand, and dosage. Here’s a general price comparison:

• USA: $50-$150 per vial (4ml or 20ml).
• UK: £30-£100 per vial.
• Australia: AUD 60-AUD 150 per vial.
• India: $10-$30 per vial of generic Labetalol Injection.

Storage and Handling

• Store Labetalol Injection at room temperature (20-25°C or 68-77°F).
• Protect it from light and moisture.
• Do not use the medication if it has expired or shows signs of discoloration or particles.

Side Effects of Labetalol Injection

While Labetalol Injection is generally well-tolerated, some patients may experience side effects, including:

• Common Side Effects: Dizziness, nausea, headache, and fatigue.
• Serious Side Effects: Slow heart rate, low blood pressure, difficulty breathing, and severe allergic reactions.

If you experience any severe side effects, seek medical attention immediately. For a complete list of side effects, refer to Drugs.com.

Prescription Requirements

Labetalol Injection is a prescription-only medication in most countries. It is typically administered by healthcare professionals in hospital settings. For home use, a valid prescription from a licensed healthcare provider is required.

Other Medications Associated with Labetalol

If you are prescribed Labetalol Injection, you may also be interested in the following related medications:

• Metoprolol Injection
• Esmolol Injection
• Propranolol Injection

Conclusion

Labetalol Injection is a life-saving medication used to manage severe hypertension and hypertensive emergencies. Whether you are buying it in the USA, UK, Australia, or importing from India, it is essential to follow your healthcare provider’s instructions and purchase from reputable sources. Always be aware of the potential side effects and storage requirements to ensure the medication’s efficacy and safety.

For more information, consult authoritative sources like the FDA, WHO, or NHS.