📋 Product Overview Table
| 🌐 Specification | 🧾 Details |
|---|---|
| 💊 Active Ingredients | Naltrexone Hydrochloride 8mg + Bupropion Hydrochloride 90mg |
| 🧪 Formulation | Fixed-dose combination (FDC) tablet |
| 🏭 Manufacturer | Kachhela Medex Pvt. Ltd. |
| 💊 Dosage Form | Oral Tablet |
| 📦 Packaging | 10 tablets per strip |
| 🩺 Indication | Weight Management in Obese or Overweight Adults |
| 🇺🇸 US Brand Equivalent | Contrave (by Currax Pharmaceuticals) |
| ⏱️ Delivery Time | 6 to 15 days |
🧬 Introduction – What is Lodonak BP?
Lodonak BP is a dual-acting pharmaceutical developed by Kachhela Medex Pvt. Ltd. that contains Naltrexone 8mg and Bupropion 90mg. It mimics the formulation of the US FDA-approved brand Contrave, and is primarily used as part of a comprehensive weight-loss plan.
This fixed-dose combination works through two synergistic mechanisms: Naltrexone affects opioid receptors to reduce food cravings, while Bupropion, an atypical antidepressant, stimulates the hypothalamus to suppress appetite and boost energy expenditure. Lodonak BP is suited for adults with a BMI ≥30, or BMI ≥27 with risk factors like diabetes or high cholesterol.
🎥 Video Overview – Dual Action Weight Loss Support
📺 “How Naltrexone + Bupropion Combos Like Lodonak BP Aid in Weight Loss“
🎬 Video Placeholder – Covers how Lodonak BP affects appetite control and metabolic pathways.
Always use under a doctor’s guidance. This is not an over-the-counter supplement.
🔬 Mechanism of Action
| 🧪 Ingredient | 🎯 Primary Function |
|---|---|
| Naltrexone 8mg | Opioid antagonist; reduces cravings and food reward response |
| Bupropion 90mg | Dopamine/norepinephrine reuptake inhibitor; suppresses appetite and boosts energy |
These two compounds act on the hypothalamic hunger center and reward systems, helping reduce emotional eating and promote better adherence to a low-calorie diet.
💡 Dosage Guidelines (As Prescribed)
| 📆 Week | 💊 Dosage (Per Day) |
|---|---|
| Week 1 | 1 tablet in the morning |
| Week 2 | 1 tablet in the morning, 1 tablet in the evening |
| Week 3+ | 2 tablets per day (as prescribed) |
Treatment duration depends on patient progress and physician evaluation.
⚠️ Side Effects & Safety Information
| 💥 Common Side Effects | ❗ Serious Risks (Rare) |
|---|---|
| Nausea, constipation | Increased blood pressure |
| Insomnia, dry mouth | Seizures (especially with high doses) |
| Headache, dizziness | Suicidal thoughts in patients with depression |
Contraindications: Epilepsy, eating disorders, uncontrolled hypertension, opioid dependence.
🧃 Storage & Handling
- Store below 30°C in a dry place
- Keep out of reach of children
- Protect from direct sunlight and moisture
🌍 Global Availability & Import Notes
| 🌎 Region | 📦 Import Policy | 📋 Prescription Requirement |
|---|---|---|
| 🇺🇸 USA | Personal import allowed for equivalents | Yes |
| 🇬🇧 UK | Import for personal use with prescription | Yes |
| 🇦🇺 Australia | Requires valid prescription and TGA approval | Yes |
🔗 Related Products (Internal Links)
| 💊 Product Name | 🏭 Manufacturer | 📖 Description |
|---|---|---|
| Contraburn 8/90mg | Kachhela Medex Pvt. Ltd. | Another Naltrexone/Bupropion combo used for weight management |
| Obelit 120mg | Intas Pharmaceuticals Ltd | Orlistat capsule that blocks fat absorption |
| Slimtop 120mg | Healing Pharma | Weight-loss aid containing Orlistat |
| AyurSlim 60 Tablets | Himalaya Drug Company | Herbal weight management supplement |
| Reeshape 120mg | Meyer Organics | Alternative Orlistat formulation for obesity treatment |
📚 Scientific & Medical References
- FDA – Contrave Prescribing Info
- PubMed – Naltrexone/Bupropion Research
- Drugs.com – Contrave Profile
- Mayo Clinic – Obesity Medications
- Himalaya Wellness – Herbal Weight Control
🩺 Expert Insight – Dr. Mira Kapoor, MD (Metabolic Medicine)
“Combining naltrexone with bupropion offers a unique dual mechanism: appetite regulation and craving control. While highly effective for committed patients, Lodonak BP must be prescribed cautiously, especially in patients with hypertension or mood disorders.”
⚠️ Disclaimer
This article is for informational use only and does not replace professional medical advice. Lodonak BP should only be used under medical supervision. Availability and legality vary by country.

