Omnacortil 40mg

🌟 Quick Reference Table

🌍 Introduction: Omnacortil 40mg in Critical Care

Omnacortil 40mg, manufactured by Macleods Pharmaceuticals, is a high-dose corticosteroid containing prednisolone, prescribed for severe inflammatory and autoimmune conditions like acute asthma attacks, systemic lupus erythematosus (SLE), and adrenal insufficiency. This potent formulation provides rapid immune suppression and inflammation control, making it indispensable in emergency and chronic care. Macleods’ commitment to affordability ensures global access to this life-saving medication under strict medical supervision.

🔬 Chemical Composition & Mechanism

• Active Ingredient: Prednisolone (40mg), a synthetic glucocorticoid.

• Excipients: Lactose monohydrate, maize starch, magnesium stearate.

• Mechanism: Binds to glucocorticoid receptors, inhibiting inflammatory cytokines (IL-1, TNF-α) and immune cell proliferation.

🌐 Global Availability & Pricing

United States

• Brands: Orapred® (Marathon Pharma), generic Prednisolone.

• Prescription: Required.

• Price: $1–$4 per tablet.

India

• Brands: Omnacortil (Macleods), Wysolone (Wyeth).

• OTC Status: Prescription-only.

• Price: ₹30–₹100 per tablet.

United Kingdom

• NHS Guidelines: Prescribed for acute adrenal crises and lupus flares.

• Price: £0.50–£2 per tablet.

Australia

• TGA Approval: Yes.

• Price: AUD 1–4 per tablet.

📊 Price Comparison (Per 40mg Tablet)

🏭 Manufacturer Spotlight: Macleods Pharmaceuticals

• Founded: 1986 in Mumbai, India.

• Reputation: Leading Indian pharma company with 150+ global approvals.

• Certifications: WHO-GMP, USFDA, UKMHRA-compliant manufacturing.

• Focus: Affordable critical care medications for chronic and acute conditions.

💊 Dosage & Administration

✅ Adults:

• Acute Asthma: 40–60mg daily for 5–7 days, then taper.

• Lupus Flares: 40mg daily for 1–2 weeks, adjusted based on response.

⚠️ Contraindications:

• Active infections (viral/bacterial/fungal), peptic ulcers, uncontrolled diabetes.

• Never stop abruptly: Taper by 5–10mg weekly to prevent adrenal crisis.

📦 Storage:

• 🌡️ Store below 25°C in a dry, dark place.

• 🔒 Keep away from children and moisture.

⚠️ Side Effects & Precautions

🩺 Expert Review: Dr. Anjali Mehta, MD (Immunology)

*“Omnacortil 40mg is crucial for managing life-threatening inflammation, but its high-dose use demands vigilant monitoring for infections and metabolic changes. Macleods’ formulation is reliable, but patient education on gradual tapering is essential.”*

🔗 Internal Links to Indian Steroids

1. Medrol 16mg: Methylprednisolone for acute allergic reactions.

📜 Trusted References

• FDA Prednisolone Safety Alerts

• WHO Guidelines for Steroid Use

• NHS High-Dose Steroid Advice

❓ FAQs

Q: How long can I take Omnacortil 40mg safely?
A: Typically 1–2 weeks for acute conditions. Long-term use requires bone density monitoring.

Q: Can I split the 40mg tablet for lower doses?
A: No—tablets are not scored. Use prescribed strengths for accurate dosing.

Q: Is Omnacortil 40mg used for COVID-19 treatment?
A: Yes, in severe cases under hospital supervision to reduce cytokine storms.