Name: Peroclin 2.5% Gel
SKU: 23208
Availability: InStock

✅ Active Ingredient Overview Table:

🔬 Active Ingredients:	Benzoyl Peroxide 2.5% w/w, Clindamycin Phosphate 1% w/w
💊 Indication:	Acne Vulgaris (Comedonal & Inflammatory Lesions)
🇺🇸 US Brand Equivalent:	Benzaclin (Benzoyl Peroxide/Clindamycin)
🏭 Manufacturer:	Wallace Pharmaceuticals Pvt. Ltd. (Founded: 1977)
📦 Packaging:	15 g Tube
🚚 Delivery Time:	6–15 days

🌿 What is Peroclin 2.5% Gel?

Peroclin 2.5% Gel combines 2.5% benzoyl peroxide (BPO) with 1% clindamycin in a lightweight gel vehicle designed to treat mild to moderate acne. Benzoyl peroxide targets Propionibacterium acnes by releasing free radicals that oxidize bacterial proteins, simultaneously providing keratolytic action to prevent follicular hyperkeratinization. Clindamycin, a lincosamide antibiotic, inhibits bacterial protein synthesis, reducing inflammation and lesion counts.

Acne patients often experience clogged pores, inflammatory papules, pustules, and comedones that can lead to scarring and hyperpigmentation. Peroclin’s dual-action formula tackles both the bacterial colonization and abnormal keratin buildup. Clinical studies show that combination therapy decreases lesion counts more rapidly than monotherapy, with improvements visible within 4–6 weeks of consistent use.

🧬 Pharmacology & Mechanism of Action

Component	Mechanism
Benzoyl Peroxide 2.5%	Releases reactive oxygen species → bactericidal against P. acnes; mild keratolytic by exfoliating follicular epithelium
Clindamycin 1%	Binds to 50S ribosomal subunit → inhibits bacterial protein synthesis → bacteriostatic/bactericidal against anaerobic skin flora
Gel Vehicle	Facilitates even distribution, enhances skin penetration, and minimizes residue

💡 Indications & Application Guidelines

Condition	Application
Acne Vulgaris	• Wash and pat skin dry with gentle cleanser. • Apply a thin layer of Peroclin Gel to affected areas once daily at bedtime. • If tolerated, increase to twice daily (morning & evening). • Use for at least 8–12 weeks to assess full efficacy.

Avoid contact with eyes, lips, nostrils, and mucous membranes. Use a non-comedogenic moisturizer to mitigate dryness. If irritation occurs, reduce frequency or discontinue temporarily.

⚠️ Warnings & Side Effects

Common:

Erythema (redness), dryness, peeling
Transient burning or stinging sensation upon application

Less Common:

Contact dermatitis
Hypersensitivity reactions (rash, swelling)

Precautions:

Conduct patch test if sensitive skin. – Use broad-spectrum sunscreen during daytime; benzoyl peroxide may increase photosensitivity. – Avoid contact with dyed fabrics or hair—may cause bleaching. – Discontinue if severe irritation or allergic reaction occurs and consult a dermatologist.

🏥 Storage Instructions

Store Peroclin Gel at 20–25°C (68–77°F) in its original tube. Protect from light and moisture. Ensure cap is tightly closed after each use. Keep out of reach of children and pets.

🌐 Availability & Purchasing

United States: Prescription-only combination gels (Benzaclin) widely available. – United Kingdom & EU: Prescription required; generic BPO/clindamycin combos accessible. – Australia: TGA-approved; prescription required.

Importing Peroclin from India may offer cost savings. Ensure compliance with local import regulations and maintain valid prescription documentation to avoid customs delays.

🔗 Internal Links to Authoritative Resources

🔗 Related Topical Acne Therapies (Indian Brands)

Clindac A Gel – Clindamycin Phosphate 1% gel for inflammatory acne.
Benzac 5% Gel – Benzoyl Peroxide 5% gel for acne therapy.
Aziderm 10% Gel – Azelaic Acid 10% gel for acne and rosacea.

🎥 Educational Video on Combination Acne Therapy

👨‍⚕️ Expert Insight: Dr. Anjali Mehta, Dermatologist

“Combination gels like Peroclin harness the complementary mechanisms of benzoyl peroxide and clindamycin to rapidly reduce bacterial load and prevent follicular plugging. Early improvements are seen within weeks, but full benefits manifest by three months.”