Name: Proluton Depot 500mg
SKU: 24657
Availability: InStock

📋 Product Overview Table

🌐 Specification	🧾 Details
💊 Product Name	Proluton Depot 500 mg Injection
🧬 Active Ingredient	Hydroxyprogesterone Caproate
🏭 Manufacturer	German Remedies Private Ltd
💡 Indication	Preterm birth prevention, luteal support, hormonal therapy
🇺🇸 US Brand	Makena
📦 Packaging	2 ml in 1 vial
🌍 Country of Origin	India
⏱️ Delivery Time	6 to 15 business days

🧬 Introduction – What is Proluton Depot 500 mg?

Proluton Depot 500 mg Injection contains Hydroxyprogesterone Caproate, a synthetic progestin primarily used to reduce the risk of preterm labor in women with a history of spontaneous preterm birth. This medication is also used in various gynecological and fertility-related hormonal therapies. Produced by German Remedies Pvt. Ltd, this injectable formulation offers long-acting progesterone support via intramuscular administration.

With a wide range of clinical applications, Proluton is recommended in both fertility clinics and obstetrics settings globally.

🎥 Educational Video Section

📺 “Progestin Therapy for Preterm Birth Prevention“
🎬 Video Placeholder – Mechanism, administration technique, and patient guidance

💬 Reviewed by: Dr. Neha Bansal, MD (Gynecology and Maternal-Fetal Medicine)

🧪 Mechanism of Action

🔬 Function	💡 Outcome
Prolongs luteal function	Maintains pregnancy and prevents spontaneous contractions
Anti-inflammatory effect	Reduces cytokine activity related to preterm labor
Hormonal support	Replaces progesterone deficit in infertility or hormonal imbalance

💊 Indications & Dosage

🩺 Indication	💉 Dosage Recommendation
Preterm birth prevention	250–500 mg IM weekly or biweekly from 16–37 weeks gestation
Assisted reproductive treatment	250–500 mg IM every 5–7 days during luteal phase
Hormonal support or amenorrhea	250–500 mg IM once every 2–4 weeks, based on condition

⚠️ Side Effects & Warnings

💥 Common Side Effects	❗ Serious Adverse Reactions
Injection site pain	Thromboembolism, Hypertension
Headache or dizziness	Depression or mood changes
Breast tenderness	Hepatic dysfunction

Caution: Not recommended for use in patients with active thromboembolic disease, hormone-sensitive cancers, or liver disease.

🧃 Storage Guidelines

Store below 25°C (77°F)
Protect from light
Do not freeze
Shake well before use

🌍 Global Availability & Import Policy

🌎 Region	🚚 Import Rules	📜 Prescription Needed
🇺🇸 USA	FDA allows import for personal use with a valid prescription	✅ Yes
🇬🇧 UK	Allowed for personal therapeutic use under MHRA regulation	✅ Yes
🇦🇺 Australia	TGA-compliant import supported under personal use permit	✅ Yes

🔗 Indian Alternatives

💊 Product	🏭 Manufacturer	📘 Description
Susten 500 mg Injection	Sun Pharma	IM progesterone used for pregnancy support and fertility treatments
Gestone Injection	Ferring Pharmaceuticals	Injectable progesterone for ART and luteal phase support
Lupigest 500 Injection	Lupin Ltd	Micronized progesterone in oil base ideal for hormone therapy
Endogest Injection	Cipla Ltd	Progesterone for high-risk pregnancies and reproductive hormone balance
Proluton 250 mg	German Remedies Pvt. Ltd	Lower dose option for preterm labor prevention

📚 References & External Resources

🩺 Expert Insight – Dr. Neha Bansal, MD

“Hydroxyprogesterone caproate remains a mainstay in preventing preterm birth among high-risk mothers. Proluton 500 mg is a trusted Indian formulation used by fertility specialists globally.”

⚠️ Disclaimer

This content is for informational purposes only and not a substitute for medical advice. Always consult a licensed healthcare provider before starting hormonal therapy like Proluton 500 mg.