Soliten 10 mg

Solifenacin

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Soliten 10 mg
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Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name): Solifenacin Succinate
💊 Indication: Overactive Bladder (OAB): Urgency, Frequency, Urge Incontinence
🇺🇸 US Brand: Vesicare
🏭 Manufacturer: Sun Pharmaceutical Industries Ltd. (Founded: 1993)
📦 Packaging: 10 Tablets per Strip
🧪 Strength: 10 mg
🚚 Delivery Time: 6–15 days

🌿 What is Solifenacin 10 mg (Soliten)?

Soliten contains 10 mg Solifenacin Succinate, a targeted M3 muscarinic receptor antagonist that reduces involuntary detrusor contractions, alleviating symptoms of overactive bladder (OAB). Clinical trials demonstrate significant reductions in urinary urgency and incontinence episodes with once-daily 10 mg dosing.

Compared to lower doses, Soliten 10 mg offers enhanced symptom control, with up to 75% reduction in leakage events. It maintains stable plasma levels for 24-hour efficacy.


🧬 Pharmacology & Mechanism of Action

Attribute Detail
Formula C23H26N2O2•2HCl
Weight 480.38 g/mol (succinate salt)
Bioavailability ~90%
Metabolism Hepatic (CYP3A4)
Half-Life ~45–68 hours

Solifenacin selectively antagonizes the M3 receptors in the bladder, minimizing off-target anticholinergic effects.


💡 Indications & Dosing

Condition Dose
OAB Symptoms 10 mg once daily; take with water; may be taken with or without food

Reduce to 5 mg in patients with moderate hepatic or severe renal impairment.


⚠️ Warnings & Side Effects

Common:

  • Dry mouth
  • Constipation
  • Headache

Serious:

  • Urinary retention
  • Narrow-angle glaucoma exacerbation
  • QT prolongation (rare)

Contraindicated in urinary retention, gastric retention, uncontrolled narrow-angle glaucoma, and severe hepatic impairment. Monitor patients for anticholinergic side effects.


🏥 Storage Instructions

Store Soliten 10 mg at 20–25°C in original blister. Protect from moisture and light. Keep away from children.


🌐 Availability & Purchasing

  • USA: Prescription-only (Vesicare); brand and generic available.
  • UK & EU: Prescription required; generic solifenacin available.
  • Australia: Prescription and TGA approval required.

International sourcing may reduce costs; ensure compliance with regulations and valid prescription.


🔗 Related OAB Therapies


🎥 Educational Video on OAB Management


👩‍⚕️ Expert Insight: Dr. Neha Kapoor, Urologist

“Solifenacin 10 mg offers a strong therapeutic option for patients with severe OAB symptoms, providing robust reduction in urgency and incontinence with a manageable side effect profile.”


Additional Information

Active

Solifenacin

Tablets

30, 60, 90

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