✅ Active Ingredient Overview Table:
| 🔬 Active Ingredient (Generic Name): | Solifenacin Succinate |
|---|---|
| 💊 Indication: | Overactive Bladder (OAB): Urgency, Frequency, Urge Incontinence |
| 🇺🇸 US Brand: | Vesicare |
| 🏭 Manufacturer: | Sun Pharmaceutical Industries Ltd. (Founded: 1993) |
| 📦 Packaging: | 10 Tablets per Strip |
| 🧪 Strength: | 10 mg |
| 🚚 Delivery Time: | 6–15 days |
🌿 What is Solifenacin 10 mg (Soliten)?
Soliten contains 10 mg Solifenacin Succinate, a targeted M3 muscarinic receptor antagonist that reduces involuntary detrusor contractions, alleviating symptoms of overactive bladder (OAB). Clinical trials demonstrate significant reductions in urinary urgency and incontinence episodes with once-daily 10 mg dosing.
Compared to lower doses, Soliten 10 mg offers enhanced symptom control, with up to 75% reduction in leakage events. It maintains stable plasma levels for 24-hour efficacy.
🧬 Pharmacology & Mechanism of Action
| Attribute | Detail |
|---|---|
| Formula | C23H26N2O2•2HCl |
| Weight | 480.38 g/mol (succinate salt) |
| Bioavailability | ~90% |
| Metabolism | Hepatic (CYP3A4) |
| Half-Life | ~45–68 hours |
Solifenacin selectively antagonizes the M3 receptors in the bladder, minimizing off-target anticholinergic effects.
💡 Indications & Dosing
| Condition | Dose |
|---|---|
| OAB Symptoms | 10 mg once daily; take with water; may be taken with or without food |
Reduce to 5 mg in patients with moderate hepatic or severe renal impairment.
⚠️ Warnings & Side Effects
Common:
- Dry mouth
- Constipation
- Headache
Serious:
- Urinary retention
- Narrow-angle glaucoma exacerbation
- QT prolongation (rare)
Contraindicated in urinary retention, gastric retention, uncontrolled narrow-angle glaucoma, and severe hepatic impairment. Monitor patients for anticholinergic side effects.
🏥 Storage Instructions
Store Soliten 10 mg at 20–25°C in original blister. Protect from moisture and light. Keep away from children.
🌐 Availability & Purchasing
- USA: Prescription-only (Vesicare); brand and generic available.
- UK & EU: Prescription required; generic solifenacin available.
- Australia: Prescription and TGA approval required.
International sourcing may reduce costs; ensure compliance with regulations and valid prescription.
🔗 Related OAB Therapies
- Solifenacin 5 mg – lower dose.
- Tolterodine ER 4 mg – antimuscarinic.
- Mirabegron 50 mg – β3-agonist.
- Darifenacin 7.5 mg – M3-selective.
🎥 Educational Video on OAB Management
👩⚕️ Expert Insight: Dr. Neha Kapoor, Urologist
“Solifenacin 10 mg offers a strong therapeutic option for patients with severe OAB symptoms, providing robust reduction in urgency and incontinence with a manageable side effect profile.”

