๐ Product Overview Table
| ๐ Specification | ๐งพ Details |
|---|---|
| ๐ Active Ingredient | Methylprednisolone Sodium Succinate |
| ๐งช Strength | 500 mg |
| ๐ญ Manufacturer | Pfizer India Ltd |
| ๐ Form | Injection (Lyophilized Powder) |
| ๐ฆ Packaging | 2 ml in 1 vial |
| โฑ๏ธ Delivery Time | 6 to 15 days |
๐งฌ What is Solu-Medrol 500mg Used For?
Solu-Medrol 500 mg is a high-dose injectable corticosteroid containing methylprednisolone sodium succinate. It is typically used in acute medical scenarios requiring immediate and potent anti-inflammatory or immunosuppressive action. Conditions such as severe autoimmune flares, neurological emergencies (e.g., multiple sclerosis relapse), and anaphylaxis often require rapid corticosteroid support โ and Solu-Medrol delivers it with efficacy and reliability.
Pfizer India Ltd manufactures this formulation to global quality standards, and it is widely distributed in hospitals and critical care units. Its rapid absorption via IV route makes it a preferred choice for acute management protocols. Solu-Medrol 500mg is suitable for both emergency and scheduled corticosteroid therapy depending on clinical need.
๐ฅ Educational Video: Solu-Medrol 500mg โ How It Works
๐บ โManaging Acute Flare-ups with Solu-Medrol 500mgโ โ Explains IV preparation, dosing, and emergency use.
๐ฌ Video Placeholder โ Highlights correct mixing technique, administration routes, and monitoring essentials.
Note: Always use Solu-Medrol under physician supervision.
๐ฉบ Indications for Use
- Acute multiple sclerosis (MS) attacks
- Lupus nephritis or SLE flares
- Rheumatoid arthritis crisis management
- Severe asthma or COPD exacerbation
- Transplant rejection episodes
- Anaphylaxis (as adjunct therapy)
- Acute spinal cord injury (with high-dose protocol)
๐ Dosage & Administration
| ๐ฅ Condition | ๐ Recommended Dose |
|---|---|
| MS Relapse | 500 mg IV once daily for 3โ5 days |
| Autoimmune Disorders (Lupus, RA) | 250โ500 mg IV every 24โ48 hours |
| Acute Asthma | 125โ500 mg IV depending on severity |
| Spinal Cord Trauma | Per high-dose protocol (30 mg/kg) |
Administer via IV injection or infusion. Monitor glucose, blood pressure, and electrolytes during treatment.
โ ๏ธ Side Effects and Risks
| ๐ฅ Common Effects | โ Serious Complications |
|---|---|
| Headache, nausea, insomnia | Gastrointestinal bleeding, adrenal suppression |
| Water retention, acne | Psychiatric effects (mania, psychosis) |
| Elevated blood glucose | Secondary infections, sepsis |
๐ง Storage & Handling
- Store below 25ยฐC
- Do not freeze reconstituted solution
- Use immediately after preparation
- Protect from light
๐ Global Buying & Import Guide
| ๐ Country | ๐ฆ Import Eligibility | ๐ Prescription Requirement |
|---|---|---|
| ๐บ๐ธ USA | Allowed for personal use | Valid prescription required |
| ๐ฌ๐ง UK | Permitted via MHRA guidelines | Must provide licensed prescription |
| ๐ฆ๐บ Australia | Allowed under TGA exemption | Prescription or supporting document |
๐ Related Corticosteroid Products (Internal Links)
| ๐ Product Name | ๐ญ Manufacturer | ๐ Brief Description |
|---|---|---|
| Depo-Medrol Injection | Pfizer India | Long-acting steroid for intramuscular administration in inflammatory disorders. |
| Predmet Injection | Sun Pharma | Injectable methylprednisolone acetate for rapid symptom control. |
| Omnacortil Oral Tablets | Macleods Pharmaceuticals | Oral prednisone alternative for long-term immune suppression. |
| Defcort Tablets | Glenmark Pharmaceuticals | Deflazacort oral option with fewer metabolic side effects. |
| Wysolone Tablets | Pfizer India | Commonly prescribed oral corticosteroid for autoimmune and allergy-related conditions. |
๐ References & External Resources
- FDA Label โ Solu-Medrol (Methylprednisolone)
- Drugs.com โ Solu-Medrol 500mg
- WHO Model List of Essential Medicines
- PubMed โ High-dose Methylprednisolone in Autoimmune Disorders
- CDC Guidelines on Steroid Use
- NHS UK โ Corticosteroid Injection Overview
- CIDRAP โ Immunomodulatory Therapies in COVID-19
๐ฉบ Clinical Perspective โ Dr. Anita Verma, MD Rheumatology
“Solu-Medrol 500 mg is often my go-to choice during autoimmune exacerbations requiring fast suppression. Its short action and efficacy make it adaptable across departments โ from neurology to pulmonology and emergency care.”
โ ๏ธ Disclaimer
This article is for informational purposes only. Solu-Medrol 500mg should be used under licensed medical supervision. Import subject to national laws and valid prescriptions.





