Metadoxine 500mg

Name: Viboliv 500mg
SKU: 27054
Availability: InStock

Viboliv • 10 Tablets per Blister by Dr. Reddy’s

Pharmaceutical-grade hepatoprotective and detoxifying agent by Dr. Reddy’s Laboratories •
Accelerates ethanol metabolism • Reduces acetaldehyde toxicity • Protects hepatocytes • Supports recovery in alcoholic liver disease, fatty liver, and enzyme elevation

💊 VIBOLIV (METADOXINE) BY DR. REDDY’S

🏭

Manufactured by Dr. Reddy’s Laboratories

Dr. Reddy’s is a global pharmaceutical leader known for high-quality generics. Viboliv (Metadoxine 500mg) is a
hepatoprotective formulation that combines pyridoxine (Vitamin B6) and pyrrolidone carboxylate (PCA).
It accelerates the elimination of ethanol and acetaldehyde, reduces oxidative stress, and helps restore liver function.

📦 Product Specifications

Generic Name
Metadoxine

Brand Name
Viboliv

Dosage Strength
500 mg per tablet

Packaging
10 tablets per blister

Manufacturer
Dr. Reddy’s Laboratories

Drug Class
Hepatoprotective / Detoxificant

Composition
Metadoxine (Pyridoxine + PCA)

Therapeutic Use
Alcoholic liver disease, fatty liver

🎯 Why Choose Metadoxine (Viboliv)?

⚡

Rapid Alcohol Elimination

Accelerates ethanol and acetaldehyde clearance from blood and tissues, reducing hangover severity and toxicity.

🛡️

Liver Cell Protection

Stabilizes hepatocyte membranes, reduces steatosis (fat accumulation), and prevents fibrosis progression.

🧪

Lowers Liver Enzymes

Clinically proven to reduce elevated ALT, AST, and GGT levels in alcoholic and non-alcoholic fatty liver.

🧠

Cognitive Support

Improves attention and memory in patients with alcohol dependence by reducing acetaldehyde brain toxicity.

⚠️

PRIMARY INDICATIONS FOR METADOXINE 500MG

Viboliv is indicated for:

Alcoholic liver disease (ALD) – acute and chronic
Fatty liver (steatosis) of various origins
Drug-induced liver injury (supportive therapy)
Hangover syndrome – accelerates detoxification
Elevated liver enzymes (ALT/AST/GGT)
Alcohol withdrawal – reduces craving and withdrawal symptoms

Dosage: Typically 1 tablet twice daily (morning and evening) for 3-6 months depending on severity.
For acute alcohol intoxication: 1-2 tablets as a single dose. Always follow medical advice.

🔬 How Metadoxine Works

Dual Action Mechanism

Pyridoxine (Vitamin B6): Cofactor for enzymes involved in amino acid metabolism and neurotransmitter synthesis; essential for liver detox pathways.
Pyrrolidone carboxylate (PCA): Accelerates acetaldehyde dehydrogenase activity, speeding up conversion of toxic acetaldehyde to acetate.
Combined effect: Increases hepatic glutathione, reduces oxidative stress, and stabilizes cell membranes.

Key Pharmacokinetics

Onset of action: 1-2 hours after oral intake
Half-life: 40-60 minutes (rapidly acting)
Excretion: Renal (urine)
Bioavailability: 60-80% after oral administration
Tissue distribution: Highest concentrations in liver and kidney

🆚 Metadoxine vs Other Hepatoprotectants

Property	Metadoxine (Viboliv)	Silymarin (Milk Thistle)	UDCA
Primary action	Ethanol metabolism acceleration	Antioxidant, anti-inflammatory	Bile acid replacement
Best for	Alcoholic liver disease, hangover	Toxin-induced liver damage	Cholestasis, PBC
Enzyme reduction speed	Rapid (days to weeks)	Moderate (weeks)	Slow (months)
Addiction support	Reduces alcohol craving	No	No

Note: Metadoxine is particularly effective when alcohol is still in the system, making it unique among hepatoprotectants.

📋 Typical Viboliv Protocols

🍷 Active Drinking / Hangover

Acute intoxication: 1-2 tablets as single dose
Hangover prevention: 1 tablet before drinking, 1 tablet after
Detox support: 1 tablet twice daily for 3-7 days
Goal: Rapid acetaldehyde clearance

🩺 Chronic Liver Disease

Dosage: 500 mg (1 tablet) twice daily
Duration: Minimum 3 months, up to 6 months
Monitor: ALT, AST, GGT every 4-6 weeks
Combine with: abstinence, B-complex, lifestyle changes

🧪 Elevated Liver Enzymes (non-alcoholic)

Dosage: 500 mg twice daily
Evaluation: Recheck enzymes after 30 days
Maintenance: 500 mg once daily if enzymes normalize
Note: Address underlying cause (diet, meds, toxins)

✅

Excellent Safety Profile

Metadoxine is generally well-tolerated. Rare side effects may include:

Mild gastrointestinal disturbances (nausea, diarrhea) – usually transient
Allergic skin reactions (rash, itching) – very rare
Peripheral neuropathy with prolonged high-dose use (extremely rare)

Contraindications: Hypersensitivity to any component. Use with caution in pregnancy/lactation only if clearly needed.
No known major drug interactions.

Order Viboliv 500mg — Metadoxine by Dr. Reddy’s

High-quality hepatoprotective tablets for liver health, alcohol detox, and enzyme control. Manufactured by Dr. Reddy’s.

💊 Metadoxine 500mg

🏭 Dr. Reddy’s

⚡ 10 Tablets/blister

💊 Buy Viboliv 500mg

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⚠️ Important Medical Information

Metadoxine is a prescription medication in many countries. It is indicated for the treatment of alcoholic liver disease and acute alcohol intoxication.
Off-label use for hangover or general liver protection should be discussed with a healthcare provider.
Not a substitute for alcohol abstinence. If you have liver disease, consult a specialist before use.
Monitor liver function tests regularly during prolonged therapy. This product contains metadoxine 500mg per tablet.
Keep out of reach of children. This information is for educational purposes only and does not replace professional medical advice.

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Additional Information

Tablets's	30, 60, 120

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