| Category | Details |
|---|---|
| Active Ingredients | Sacubitril 97 mg + Valsartan 103 mg per tablet (200 mg total) |
| Indication | Chronic Heart Failure (NYHA Class II-IV) |
| US Brand | Entresto (Novartis) |
| Manufacturer | Novartis India Ltd. (Part of Novartis AG) |
| Packaging | 7 tablets/strip |
| Strength | Sacubitril 97 mg + Valsartan 103 mg |
| Delivery Time | 6โ15 days |
๐ย Introduction to Vymada 200 mg (Sacubitril/Valsartan)
Vymada 200 mg byย Novartis Indiaย is aย dual-action therapyย combiningย Sacubitrilย (neprilysin inhibitor) andย Valsartanย (ARB) to treat chronic heart failure. This innovative combo reduces strain on the heart by blocking harmful hormones (angiotensin II) and enhancing protective ones (natriuretic peptides). Clinical trials show itย lowers hospitalization risk by 20%ย andย cuts cardiovascular deaths by 16%ย compared to traditional therapies. Packaged in 7-tablet strips, Vymada offers a cost-effective alternative to Entresto, adhering to WHO-GMP standards.
๐งชย Chemical Composition
| Component | Role |
|---|---|
| Sacubitril | Neprilysin inhibitor (97 mg) |
| Valsartan | Angiotensin II receptor blocker (103 mg) |
| Microcrystalline Cellulose | Binder/Stabilizer |
| Magnesium Stearate | Lubricant |
๐ญย Manufacturer Spotlight: Novartis India
Novartis India, a subsidiary of Swiss pharma giantย Novartis AG, is a leader in cardiovascular and oncology therapies. Founded in 1996, it operates underย WHO-GMP, USFDA, and EU-GMPย standards, exporting to 50+ countries. Vymada reflects its commitment to cutting-edge, affordable care.
๐ย How to Buy Vymada in the US, Australia & UK
United States:
-
Prescription Required:ย Yes (FDA-approved Entresto costsย 500โ600/month).
-
Cost Savings:
Source Price (28 tablets) US Brand (Entresto) 500โ600 Vymada (India) 50โ100
Australia/UK:
๐กย Dosage & Usage
Recommended Dosage:
-
Starting Dose:ย 49/51 mg twice daily (titrate to 97/103 mg).
-
Maintenance:ย 200 mg (Sacubitril/Valsartan) twice daily.
Usage Tips:
๐ Takeย 1 hour before/2 hours after mealsย for optimal absorption.
๐ Avoid potassium supplements (risk of hyperkalemia).
โ ๏ธย Side Effects & Precautions
| Common Effects (โค15% Users) | Rare Risks (โค2% Users) |
|---|---|
| Dizziness | Angioedema (facial swelling) |
| Hyperkalemia | Kidney dysfunction |
FDA Warning:ย Contraindicated in pregnancy (fetal toxicity) or with ACE inhibitors (FDA).
๐ย Internal Links to Indian Brands
-
Valzaar:ย Valsartan by Torrent Pharma.
-
Cardivas:ย Carvedilol for heart failure.
-
Lasix:ย Furosemide for edema.
-
Zyloric:ย Allopurinol for gout.
๐ฉบย Expert Opinion: Dr. Arjun Patel
*โVymadaโs dual mechanism revolutionizes heart failure management. Novartisโ formulation matches Entrestoโs efficacy but at 80% lower cost, making it a game-changer for patients needing long-term therapy.โ*
โ Dr. Arjun Patel, Cardiologist, Kokilaben Dhirubhai Ambani Hospital, Mumbai
๐ฆย Storage Guide
| Condition | Requirement | Icon |
|---|---|---|
| Temperature | Below 30ยฐC | ๐ก๏ธ |
| Moisture | Keep in original strip | ๐ก๏ธ |
| Light | Avoid exposure | ๐ |
๐ย Prescription Requirements
-
US/UK/AU:ย Mandatory. Use platforms likeย Practoย for online consultations.
๐ย Price Comparison: India vs. Global
| Country | Price (28 tablets) | Savings vs. US |
|---|---|---|
| India | โน3,000โโน5,000 (40โ67) | 80โ85% |
| USA | 500โ600 | โ |
| UK | ยฃ400โยฃ500 | 75โ80% |
| Australia | AUD 600โAUD 800 | 70โ75% |
Authoritative Resources:
๐ Pro Tip:ย Pair Vymada withย low-sodium dietsย andย daily weight monitoringย to manage heart failure effectively!





