✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Imiquimod
💊 Indication:	Actinic Keratosis, Superficial Basal Cell Carcinoma, External Genital Warts
🇺🇸 US Brand:	Aldara
🏭 Manufacturer:	Glenmark Pharmaceuticals Ltd. (Founded: 1977)
📦 Packaging:	0.25 g Sachet
🧪 Strength:	5% w/w
🚚 Delivery Time:	6–15 days

🌿 What is Imiquimod 5% (Imiquad Sachet)?

Imiquad Sachet delivers a 5% imiquimod cream in pre-measured 0.25 g packets designed for precise topical application. Imiquimod is an immune response modifier that stimulates Toll-like receptor 7, inducing cytokines (IFN-α, TNF-α, IL-12) to promote antiviral and antitumor activity.

This mechanism harnesses the body’s innate immunity to clear abnormal skin cells and viral infections. Actinic keratoses patients experience gradual lesion erythema and resolution over weeks, while genital wart treatment leads to wart regression via localized immune activation. Imiquad’s sachet format ensures accurate dosing, minimizes waste, and enhances patient adherence.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C14H16N4O3
Molecular Weight	240.31 g/mol
Mode of Action	TLR7 agonist → cytokine induction → immune-mediated clearance
Local Activity	Induces apoptosis in dysplastic/viral-infected cells

💡 Indications & Application Guidelines

Condition	Regimen
Actinic Keratosis (AK)	Apply 5% cream 3× weekly for 4 weeks; wash off after 8–10 hrs
Superficial BCC	Apply 5% cream 5× weekly for 6 weeks; wash off after 8–10 hrs
External Genital Warts (AGW)**	Apply 5% cream 3× weekly for up to 16 weeks; wash off after 6–10 hrs

Use gloves to avoid mucosal exposure. Schedule treatments to minimize irritation and monitor local skin reactions.

⚠️ Warnings & Side Effects

Common:

Local skin reactions: erythema, erosion, pruritus, edema
Flu-like symptoms (rare)

Serious (rare):

Severe local inflammation requiring treatment interruption
Systemic symptoms: fever, myalgia, lymphadenopathy

Advise patients on expected erythema and treatment pauses if severe erosions develop. Contraindicated in immunocompromised individuals without specialist oversight.

🏥 Storage Instructions

Store Imiquad Sachets at 20–25°C. Protect from light and moisture. Keep packets sealed until use and out of reach of children.

🌐 Availability & Purchasing

USA: Prescription-only (Aldara); compounding alternatives available.
UK & EU: Prescription required; generic imiquimod formulations accessible.
Australia: Schedule 4; prescription use only.

Glenmark’s sachet format offers cost-effective dosing. Ensure compliance with local guidelines and specialist prescription.

🎥 Educational Video on Imiquimod Therapy

👨‍⚕️ Expert Insight: Dr. Meera Rao, Dermatologist

“Imiquad’s sachet dosing ensures precise imiquimod delivery, optimizing efficacy and minimizing waste. Patient education on expected local reactions drives adherence and successful outcomes.”