📋 Product Overview Table

🌐 Specification	🧾 Details
💊 Active Ingredient	Clomiphene Citrate 25 mg
🧪 Formulation	Selective Estrogen Receptor Modulator (SERM)
🏭 Manufacturer	Serum Institute of India
💊 Dosage Form	Oral Tablet
📦 Packaging	5 Tablets in 1 Strip
🩺 Indication	Female infertility, anovulation, PCOS-related ovulatory disorders
🇺🇸 US Brand Equivalent	Clomid
⏱️ Delivery Time	6 to 15 days

🧬 Introduction – What is Siphene 25mg (Clomiphene)?

Siphene 25mg, manufactured by the Serum Institute of India, contains Clomiphene Citrate, a widely used fertility medication that belongs to the class of Selective Estrogen Receptor Modulators (SERMs). It is primarily prescribed for women who are experiencing infertility due to anovulation (lack of ovulation), especially those diagnosed with Polycystic Ovary Syndrome (PCOS).

Unlike many fertility treatments that require injections, Siphene is taken orally, making it more convenient and less invasive. Clomiphene works by stimulating the pituitary gland to release more follicle-stimulating hormone (FSH) and luteinizing hormone (LH), thereby inducing ovulation. The 25mg dosage is often used in patients who are sensitive to higher strengths or are starting treatment for the first time.

This low-dose formulation is also utilized in mild ovarian stimulation protocols, particularly in assisted reproductive technologies such as IUI (Intrauterine Insemination) or early-stage IVF cycles. It is considered cost-effective, safe, and has a long-standing track record in clinical fertility practice across the globe.

🎥 Video Overview – Fertility Boost with Clomiphene

📺 “How Siphene 25mg Helps Restore Ovulation“

🎬 Video Placeholder – Covers mechanism, treatment cycle, and expectations from Clomiphene therapy.

Always consult your reproductive endocrinologist before beginning ovulation induction therapy.

🔬 Mechanism of Action & Pharmacological Profile

🧪 Parameter	📊 Details
Drug Class	Selective Estrogen Receptor Modulator (SERM)
Mechanism	Estrogen receptor blockade in hypothalamus
Target Hormones	Increases FSH & LH release
Time to Ovulation	Typically 5–10 days after last tablet
Half-Life	5–7 days
Administration Duration	5 days per cycle (usually Day 2–6 or 3–7)

💡 Dosage & Treatment Guidelines

📅 Cycle Day	💊 Dosage	📌 Notes
Day 2 to Day 6	25mg once daily	Low-dose regimen, monitored via ultrasound
Day 3 to Day 7	25mg once daily	Alternate starting day depending on doctor’s protocol

Monitoring ovulation with ultrasound or LH testing is recommended to optimize results.

⚠️ Side Effects & Warnings

💥 Common Side Effects	❗ Serious Risks (Rare)
Hot flashes, mood swings	Ovarian Hyperstimulation Syndrome (OHSS)
Abdominal bloating	Visual disturbances
Nausea, breast tenderness	Ovarian cyst formation

Contraindications:

Pregnancy
Liver disease
Ovarian cysts not due to PCOS

🧃 Storage Guidelines

Store below 25°C (77°F)
Keep away from moisture and direct sunlight
Do not use expired tablets

🌍 Availability & Import Info

🌎 Country	📦 Import Status	📋 Prescription Required
🇺🇸 USA	Allowed via FDA personal import rules	✅ Yes
🇬🇧 UK	Permitted under MHRA personal use	✅ Yes
🇦🇺 Australia	TGA allows with doctor’s prescription	✅ Yes

🔗 Related Fertility Medications

💊 Product Name	🏭 Manufacturer	📖 Description
Clomiford 50mg	Healing Pharma	Higher dose of Clomiphene for resistant ovulation cases
Fertomid 25mg	Cipla Ltd.	Alternative 25mg clomiphene citrate formulation
Clomid 50mg	Sanofi Aventis	US brand reference drug for clomiphene
Letoval 2.5mg	Sun Pharma	Letrozole-based ovulation induction for PCOS patients
Ovulet 25mg	Intas Pharmaceuticals	Used in mild ovarian stimulation protocols

📚 Trusted Medical Resources

🩺 Expert Opinion – Dr. Sneha Wadhwani, MD (Reproductive Medicine)

“Siphene 25mg is often the first step in fertility treatment due to its gentle action and well-documented results. For many women with ovulatory dysfunction, this low-dose clomiphene citrate successfully restores ovulation while minimizing risks.”

⚠️ Disclaimer

This article is intended for informational purposes only. Do not begin or adjust any fertility treatment, including Siphene (Clomiphene), without consulting a certified reproductive specialist.