✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Ibuprofen
💊 Indication:	Pain, Fever, Inflammation (Headache, Dental Pain, Musculoskeletal Pain, Dysmenorrhea)
🇺🇸 US Brand:	Advil, Motrin
🏭 Manufacturer:	Abbott India Pvt Ltd (Founded: 1944)
📦 Packaging:	15 Tablets per Strip
🧪 Strength:	200 mg
🚚 Delivery Time:	6–15 days

🌡️ What is Ibuprofen 200 mg (Brufen)?

Brufen provides 200 mg of Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis. This leads to effective relief of pain, fever, and inflammation in conditions such as headaches, dental pain, muscle aches, and menstrual cramps.

Oral Ibuprofen is rapidly absorbed, with peak plasma concentrations reached within 1–2 hours. The 200 mg dose offers balanced efficacy and tolerability for mild to moderate pain and fever management.

For comprehensive prescribing and safety information, consult the FDA label for Motrin and the Drugs.com monograph. Additional guidance is available via the NHS Medicines A–Z entry and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C13H18O2
Molecular Weight	206.28 g/mol
Bioavailability	~80–100%
Metabolism	Hepatic (CYP2C9)
Half-Life	~2 hours

Ibuprofen’s non-selective COX inhibition reduces inflammatory mediators, providing analgesic, antipyretic, and anti-inflammatory effects.

💡 Indications & Dosing

Condition	Dose
Mild to Moderate Pain	200–400 mg every 4–6 hours as needed (max 1,200 mg/day OTC)
Fever	200 mg every 4–6 hours (max 1,200 mg/day)
Dysmenorrhea	400 mg initial, then 200 mg every 4–6 hrs (max 1,200 mg/day)

Take with food or milk to minimize gastrointestinal irritation.

⚠️ Warnings & Side Effects

Common:

Gastrointestinal discomfort (nausea, dyspepsia)
Headache, dizziness
Edema

Serious:

GI bleeding or ulceration
Increased cardiovascular risk (MI, stroke)
Renal impairment

Use the lowest effective dose for the shortest duration necessary. Monitor for GI and cardiovascular adverse events, particularly in high-risk patients.

🏥 Storage Instructions

Store Brufen 200 mg at 20–25°C in a dry place, protected from light. Keep out of reach of children.

🌐 Availability & Purchasing

USA: OTC for 200 mg; higher doses require prescription.
UK & EU: OTC availability; prescription for higher doses.
Australia: OTC for limited pack sizes; follow TGA guidelines.

Importing from India may reduce costs; ensure adherence to local regulations and valid prescription for higher doses.

🔗 Related NSAID Options

Piroxicam 20 mg – long half-life NSAID.
Celecoxib 200 mg – COX-2 selective inhibitor.

🎥 Educational Video on Ibuprofen

👨‍⚕️ Expert Insight: Dr. Priya Mehta, General Physician

“Ibuprofen 200 mg strikes a balance between efficacy and safety for everyday pain and fever relief. It’s important to counsel patients on GI precautions and proper dosing intervals.”