Cobix

🌿 What is Celecoxib (Cobix)?

Cobix contains Celecoxib, a selective COX-2 inhibitor. By blocking COX-2, it reduces prostaglandins at inflammation sites while preserving COX-1–mediated gastric protection. Consequently, Cobix offers targeted relief with lower GI risk compared to traditional NSAIDs.

🧬 Chemical Profile & Mechanism

Selecting COX-2 spares gastric mucosa, lowering ulceration risk while controlling pain.

💡 Indications & Usage

• Osteoarthritis: 100 mg twice daily or 200 mg once daily.
• Rheumatoid Arthritis: 100–200 mg twice daily.
• Ankylosing Spondylitis: 200 mg once daily.
• Acute Pain: 400 mg initial, then 200 mg as needed (max 400 mg/day).
• Dysmenorrhea: 400 mg initial, then 200 mg as needed.

💊 Dosage Guidelines

Take with food to reduce gastric irritation. Swallow capsules whole.

⚠️ Safety & Side Effects

Common:

• Diarrhea, dyspepsia
• Edema
• Hypertension

Serious:

• Cardiovascular risk (MI, stroke)
• GI bleeding
• Renal impairment

Use lowest effective dose. Monitor cardiovascular and renal status, especially in high-risk patients.

🏥 Storage Instructions

Store Cobix at 20–25°C in original packaging. Protect from moisture. Keep away from children.

🌐 Availability & Purchasing

• USA & Canada: Prescription-only; brand and generics available.
• UK & Europe: Prescription required; Celecoxib generics.
• Australia: Prescription and TGA approval for some strengths.

Importing from India may cut costs; ensure regulatory compliance and valid prescription.

🔗 Related Medications

• Meloxicam 15 mg – preferential COX-2 inhibitor.
• Etoricoxib 60 mg – COX-2 inhibitor.
• Ibuprofen 400 mg – non-selective NSAID.
• Diclofenac SR 75 mg – extended-release NSAID.
• Naproxen SR 750 mg – sustained-release NSAID.

🎥 Educational Video on Celecoxib

👨‍⚕️ Expert Insight: Dr. Priya Mehta, Rheumatologist

“Celecoxib provides effective arthritis relief with reduced GI risk. However, its cardiovascular profile demands careful patient selection and monitoring.”