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Abhigra 100mg
Abhigra 100mg
Sildenafil Citrate
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Abhigra 100mg
Sildenafil Citrate • 10 Tablets per Strip by HAB Pharma
Pharmaceutical-grade Sildenafil Citrate 100mg by HAB Pharma •
Generic equivalent of Viagra® for the treatment of erectile dysfunction • Helps achieve and maintain erection when sexually stimulated
Generic equivalent of Viagra® for the treatment of erectile dysfunction • Helps achieve and maintain erection when sexually stimulated
💊 ABHIGRA 100MG — SILDENAFIL CITRATE BY HAB PHARMA
🏭
Manufactured by HAB Pharma
HAB Pharma is a trusted pharmaceutical company known for producing high-quality generic medications.
Abhigra 100mg contains Sildenafil Citrate, the same active ingredient as Viagra®, and is manufactured under strict quality standards.
It is a PDE5 inhibitor that helps increase blood flow to the penis, enabling an erection in response to sexual stimulation.
📦 Product Specifications
Generic Name
Sildenafil Citrate
Sildenafil Citrate
Brand Name
Abhigra
Abhigra
Dosage Strength
100 mg per tablet
100 mg per tablet
Packaging
10 tablets per strip
10 tablets per strip
Manufacturer
HAB Pharma
HAB Pharma
Drug Class
PDE5 Inhibitor
PDE5 Inhibitor
Therapeutic Use
Erectile Dysfunction
Erectile Dysfunction
Onset of Action
30–60 minutes
30–60 minutes
🔬 How Abhigra (Sildenafil) Works
Mechanism of Action
- PDE5 inhibition: Sildenafil selectively inhibits phosphodiesterase type 5 (PDE5), the enzyme responsible for breaking down cGMP in the corpus cavernosum.
- Increased blood flow: When sexual stimulation causes local release of nitric oxide (NO), PDE5 inhibition by sildenafil leads to increased cGMP levels, resulting in smooth muscle relaxation and enhanced blood inflow to the penis.
- Erection: This allows men with erectile dysfunction to achieve and maintain an erection sufficient for sexual activity .
Pharmacokinetics
- Bioavailability: ~40%
- Peak plasma: 30–120 minutes (fasting)
- Food effect: High-fat meal delays absorption by ~1 hour, reduces peak levels
- Protein binding: 96%
- Half-life: ~4 hours
- Metabolism: Liver (CYP3A4, CYP2C9)
- Excretion: 80% feces, 13% urine
💊 Dosage & Administration
Standard Dosing
- Recommended starting dose: 50 mg taken as needed, approximately 1 hour before sexual activity.
- Dose range: Based on effectiveness and toleration, dose may be increased to 100 mg or decreased to 25 mg.
- Maximum dose: 100 mg per day.
- Frequency: Maximum once per day.
- Timing window: Can be taken 30 minutes to 4 hours before sexual activity.
Special Populations – Start with 25 mg
- Elderly (≥65 years)
- Hepatic impairment (e.g., cirrhosis)
- Severe renal impairment (CrCl <30 mL/min) [citation:2][citation:3]
- Concomitant strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, erythromycin)
- Ritonavir: Max dose 25 mg in 48 hours (11-fold increased exposure)
⚠️ Important: Sexual stimulation is required for Abhigra to work – it does not cause an automatic erection [citation:3].
Take on an empty stomach for fastest absorption; a high-fat meal may delay onset [citation:3].
⚠️
CRITICAL CONTRAINDICATIONS & WARNINGS
DO NOT TAKE ABHIGRA IF:
- You take any nitrates (nitroglycerin, isosorbide mononitrate/dinitrate) – even recreationally (“poppers” like amyl nitrate). Combining can cause a sudden, dangerous drop in blood pressure leading to heart attack or stroke.
- You take guanylate cyclase stimulators (riociguat for pulmonary hypertension).
- You are allergic to sildenafil or any tablet ingredients.
- Sexual activity is inadvisable due to cardiovascular status.
❤️
Cardovascular Considerations
Sildenafil has mild vasodilatory properties, causing transient decreases in blood pressure (mean 8.4/5.5 mmHg).
Use with caution in patients with:
- Left ventricular outflow obstruction (aortic stenosis, IHSS)
- Severely impaired autonomic control of blood pressure
- Myocardial infarction, stroke, or life-threatening arrhythmia within the last 6 months
- Resting hypotension (BP <90/50 mmHg) or hypertension (BP >170/110 mmHg)
- Cardiac failure or coronary artery disease causing unstable angina
Consult your doctor if you have any cardiovascular conditions before using Abhigra.
📋 Side Effects & Precautions
Common Side Effects (≥2%)
- Headache (10-16%)
- Flushing (10%)
- Dyspepsia (indigestion) (7%)
- Nasal congestion (4%)
- Dizziness (2%)
- Nausea (2%)
- Visual disturbances (3%) – sensitivity to light, blurred vision, blue/green color tinge
Serious Adverse Events (Seek Immediate Medical Attention)
- Prolonged erection >4 hours (priapism) – can cause permanent tissue damage
- Sudden vision loss in one or both eyes (NAION)
- Sudden hearing decrease or loss
- Severe hypotension (especially with nitrates)
- Chest pain, shortness of breath – seek emergency care
💡 Precautions: Use with caution if you have anatomical deformation of the penis (angulation, Peyronie’s disease), conditions predisposing to priapism (sickle cell anemia, multiple myeloma, leukemia), bleeding disorders, or active peptic ulcer .
Avoid alcohol excessively as it may increase side effects.
🔄 Important Drug Interactions
| Drug Class / Examples | Interaction | Recommendation |
|---|---|---|
| Nitrates (nitroglycerin, isosorbide, amyl nitrate) | Severe hypotension, increased cardiac risk | CONTRAINDICATED [citation:2] |
| Alpha-blockers (doxazosin, tamsulosin) | Additive hypotensive effects | Initiate sildenafil at 25 mg |
| CYP3A4 inhibitors (ketoconazole, itraconazole, erythromycin) | ↑ sildenafil exposure (3-fold) | Consider starting dose 25 mg |
| Ritonavir (HIV protease inhibitor) | ↑↑ sildenafil exposure (11-fold) | Max 25 mg in 48 hours |
| Rifampin (CYP3A4 inducer) | ↓ sildenafil levels | Monitor efficacy, may need dose adjustment |
Order Abhigra 100mg — Sildenafil by HAB Pharma
Affordable, reliable generic alternative for erectile dysfunction treatment. Manufactured by HAB Pharma.
💊 Sildenafil 100mg
🏭 HAB Pharma
⚡ 10 Tablets/strip
⚠️ Important Medical Information
Sildenafil is a prescription medication used for erectile dysfunction. It should not be taken by individuals taking nitrates (for chest pain) or riociguat.
This product is intended for use by men over 18 years of age. Consult your healthcare provider before use, especially if you have heart disease, high or low blood pressure, liver or kidney disease,
a history of stroke, or conditions predisposing to priapism. Do not exceed the recommended dose of one tablet per day.
Seek immediate medical attention if you experience an erection lasting longer than 4 hours, sudden vision loss, or sudden hearing loss.
This information is for educational purposes only and does not replace professional medical advice. Keep out of reach of children.
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Additional Information
| active | |
|---|---|
| Tablets | 30, 60, 90 |
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