โ Active Ingredient Overview Table:
| ๐ฌ Active Ingredient (Generic Name): | Ibuprofen |
|---|---|
| ๐ Indication: | Pain, Fever, Inflammation (Headache, Dental Pain, Musculoskeletal Pain, Dysmenorrhea) |
| ๐บ๐ธ US Brand: | Advil, Motrin |
| ๐ญ Manufacturer: | Abbott India Pvt Ltd (Founded: 1944) |
| ๐ฆ Packaging: | 15 Tablets per Strip |
| ๐งช Strength: | 200 mg |
| ๐ Delivery Time: | 6โ15 days |
๐ก๏ธ What is Ibuprofen 200 mg (Brufen)?
Brufen provides 200 mg of Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis. This leads to effective relief of pain, fever, and inflammation in conditions such as headaches, dental pain, muscle aches, and menstrual cramps.
Oral Ibuprofen is rapidly absorbed, with peak plasma concentrations reached within 1โ2 hours. The 200 mg dose offers balanced efficacy and tolerability for mild to moderate pain and fever management.
For comprehensive prescribing and safety information, consult the FDA label for Motrin and the Drugs.com monograph. Additional guidance is available via the NHS Medicines AโZ entry and the WHO Essential Medicines List.
๐งฌ Pharmacology & Mechanism of Action
| Attribute | Detail |
|---|---|
| Chemical Formula | C13H18O2 |
| Molecular Weight | 206.28 g/mol |
| Bioavailability | ~80โ100% |
| Metabolism | Hepatic (CYP2C9) |
| Half-Life | ~2 hours |
Ibuprofenโs non-selective COX inhibition reduces inflammatory mediators, providing analgesic, antipyretic, and anti-inflammatory effects.
๐ก Indications & Dosing
| Condition | Dose |
|---|---|
| Mild to Moderate Pain | 200โ400 mg every 4โ6 hours as needed (max 1,200 mg/day OTC) |
| Fever | 200 mg every 4โ6 hours (max 1,200 mg/day) |
| Dysmenorrhea | 400 mg initial, then 200 mg every 4โ6 hrs (max 1,200 mg/day) |
Take with food or milk to minimize gastrointestinal irritation.
โ ๏ธ Warnings & Side Effects
Common:
- Gastrointestinal discomfort (nausea, dyspepsia)
- Headache, dizziness
- Edema
Serious:
- GI bleeding or ulceration
- Increased cardiovascular risk (MI, stroke)
- Renal impairment
Use the lowest effective dose for the shortest duration necessary. Monitor for GI and cardiovascular adverse events, particularly in high-risk patients.
๐ฅ Storage Instructions
Store Brufen 200 mg at 20โ25ยฐC in a dry place, protected from light. Keep out of reach of children.
๐ Availability & Purchasing
- USA: OTC for 200 mg; higher doses require prescription.
- UK & EU: OTC availability; prescription for higher doses.
- Australia: OTC for limited pack sizes; follow TGA guidelines.
Importing from India may reduce costs; ensure adherence to local regulations and valid prescription for higher doses.
๐ Related NSAID Options
- Piroxicam 20 mg โ long half-life NSAID.
- Celecoxib 200 mg โ COX-2 selective inhibitor.
๐ฅ Educational Video on Ibuprofen
๐จโโ๏ธ Expert Insight: Dr. Priya Mehta, General Physician
โIbuprofen 200 mg strikes a balance between efficacy and safety for everyday pain and fever relief. Itโs important to counsel patients on GI precautions and proper dosing intervals.โ





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