✅ Active Ingredient Overview Table:
| 🔬 Active Ingredient (Generic Name): | Crotamiton 10% w/w |
|---|---|
| 💊 Indication: | Scabies, Pruritus (Itchy Dermatoses) |
| 🇺🇸 US Brand Equivalent: | Eurax (Crotamiton) – Limited US availability |
| 🏭 Manufacturer: | Abbott India Pvt Ltd (Founded: 1948) |
| 📦 Packaging: | 20 g Tube |
| 🧪 Strength: | 10% w/w |
| 🚚 Delivery Time: | 6–15 days |
🌿 What is Crotorax Cream 10%?
Crotorax Cream contains 10% Crotamiton, a nonsteroidal anti-scabietic and antipruritic agent. It is primarily indicated for the topical treatment of scabies and provides symptomatic relief from itching due to various dermatoses. Crotamiton exerts a dual action: it eradicates the Sarcoptes scabiei mite and soothes pruritus by acting on peripheral cutaneous sensory nerves, interrupting the itch-scratch cycle. Formulated in a emollient cream base, Crotorax ensures effective skin penetration with minimal irritation, making it suitable for use in adults and children over 2 years.
🧬 Pharmacology & Mechanism of Action
| Attribute | Detail |
|---|---|
| Chemical Formula | C12H17NO2 |
| Molecular Weight | 199.27 g/mol |
| Mechanism | • Anti-scabietic: Inhibits choline esterase in scabies mite → paralysis and death of the mite. • Antipruritic: Modulates peripheral sensory nerve activity → reduces itching sensation. |
| Absorption | Minimal systemic absorption after topical application; most remains localized in the epidermis. |
| Metabolism | Negligible systemic metabolism due to low absorption; minimal hepatic involvement. |
| Half-Life | Not applicable for topical; minimal systemic levels detected. |
💡 Indications & Application Guidelines
| Condition | Application Regimen |
|---|---|
| Scabies (All Ages ≥2 yrs) | • Day 1: Apply Crotorax Cream 10% liberally to entire body from neck to soles, especially web spaces and flexural areas. • After 24 hours: Wash off thoroughly with soap and water. • Day 2: Repeat application in the evening; wash off next morning. |
| Pruritus (Itchy Dermatoses) | • Cleanse and dry affected area. • Apply a thin layer of Crotorax Cream to pruritic lesions 2–3 times daily until resolution. |
- Preparation: Before application, ensure skin is clean and dry; avoid areas with open wounds.
- Application: Squeeze sufficient cream; spread evenly over affected areas.
- Frequency: For scabies, apply on two consecutive nights; for pruritus, apply up to thrice daily.
- Precautions: Avoid contact with eyes, mouth, and mucous membranes. Discontinue if severe irritation or hypersensitivity occurs.
⚠️ Warnings & Side Effects
Common (Mild, Local):
- Skin irritation, redness
- Mild burning or stinging sensation
- Dryness or scaling
Less Common:
- Contact dermatitis with prolonged use
- Urticaria or rash
Serious (Rare):
- Severe allergic reaction (angioedema, anaphylaxis)
Precautions:
- Hypersensitivity: Contraindicated in patients with known allergy to Crotamiton or excipients.
- Infants & Children (<2 yrs): Safety not established; avoid use or use under specialist guidance.
- Pregnancy & Breastfeeding: Limited data; use only if benefit outweighs risk.
- Secondary Infection: If skin integrity compromised, treat infection prior to Crotamiton use.
🏥 Storage Instructions
Store Crotorax Cream at 20–25°C in its original tube. Protect from direct sunlight and excessive heat. Ensure cap is tightly closed after use. Keep out of reach of children.
🌐 Availability & Purchasing
- United States: Limited availability; prescription-based import or via specialty pharmacies.
- United Kingdom & EU: Prescription required; topical Crotamiton products are available under dermatology guidance.
- Australia: TGA-approved; prescription needed; available via PBS or private script.
Importing from India:
Purchasing Crotorax Cream from India can result in cost savings. Ensure you have a valid prescription, adhere to local personal importation regulations, and provide necessary customs documentation to avoid delays.
🔗 Internal Links to Authoritative Resources
- FDA: Scabies Treatment Medications
- Drugs.com: Crotamiton Monograph
- NHS: Scabies Overview & Management
- WHO: Skin NTDs – Scabies Guidelines
- American Academy of Dermatology: Pruritus Guidelines
🔗 Internal Links to Related Topical Therapies (Indian Brands)
- Permite Cream 5% (Permethrin) – Permethrin 5% topical by Curatio Healthcare.
- Scabper Lotion 5% – Permethrin 5% lotion by Menarini India for scabies control.
- Imiquad Sachet (Imiquimod) – Imiquimod 5% cream for molluscum contagiosum and warts by Glenmark.
- Candid B Lotion – Clotrimazole/Beclometasone combination lotion for infected and inflamed dermatoses by Glenmark.
🎥 Educational Video on Scabies & Its Treatment
👩⚕️ Expert Insight: Dr. Meera Joshi, Dermatologist
“Crotamiton 10% cream offers a well-tolerated option for scabies treatment, especially in patients sensitive to permethrin. The cream base soothes irritated skin, but strict application to all body areas is essential for complete mite eradication.”

