📋 Product Overview Table
| 🌐 Specification | 🧾 Details |
|---|---|
| 💊 Product Name | Duvadilan Retards 40 mg SR Capsules |
| 🧬 Active Ingredient | Isoxsuprine Hydrochloride (Sustained Release) |
| 🏭 Manufacturer | Abbott India Pvt. Ltd. |
| 💡 Indication | Prolonged uterine relaxation in preterm labor risk |
| 🇺🇸 US Brand | Vasodilan SR |
| 📦 Packaging | 10 sustained‑release capsules per strip |
| 🌍 Country of Origin | India |
| ⏱️ Delivery Time | 6 to 15 business days |
🧬 Introduction – What is Duvadilan Retards 40 mg?
Duvadilan Retards 40 mg is an extended‑release formulation of isoxsuprine HCl, a tocolytic that relaxes the uterus to help prevent preterm labor. Developed by Abbott India, this SR capsule ensures a steadier therapeutic level over an extended period, reducing dosing frequency and improving compliance for pregnant women at risk of early contractions.
🎥 Educational Video Overview
📺 “Extended‑Release Tocolytics: Benefits of SR Isoxsuprine”
🎬 Video Placeholder – Covers pharmacokinetics, dosing, and monitoring.
💬 Reviewed by: Dr. Rekha Sharma, MD (Maternal‑Fetal Medicine Specialist)
🔬 Mechanism of Action
| 🎯 Action | 💡 Physiological Effect |
|---|---|
| β₂‑adrenergic agonism | Sustained inhibition of uterine smooth muscle |
| Vasodilation | Improves uteroplacental perfusion |
| Slow-release delivery | Maintains stable plasma levels throughout dosing interval |
💊 Indications & Dosage
- Preterm labor prevention: 40 mg SR capsule orally once or twice daily as directed
- Uterine relaxation in obstetrics: As per specialist prescription
Use under OB‑GYN supervision. Monitor maternal heart rate and blood pressure regularly.
⚠️ Side Effects & Precautions
| 🔸 Common Side Effects | 🔸 Serious Concerns |
|---|---|
| Headache, flushing | Tachycardia, hypotension |
| Dizziness, nausea | Pulmonary edema (rare) |
| Palpitations | Cardiac arrhythmias in susceptible patients |
⚠️ Contraindicated in hypertensive, cardiac, or hyperthyroid pregnant individuals.
🧃 Storage & Handling
- Store at 20–25 °C
- Keep in original SR capsule strip
- Shield from light and moisture
- Keep away from children
🌍 Global Availability & Import Regulations
| 🌎 Region | 🚚 Import Notes | 📜 Prescription Required |
|---|---|---|
| 🇺🇸 USA | Not FDA‑approved; import under personal use policy | ✅ Yes |
| 🇬🇧 UK | Allowed with MHRA exemption for therapeutic need | ✅ Yes |
| 🇦🇺 Australia | TGA permits import via prescription | ✅ Yes |
Estimated delivery: 6–15 working days, depending on courier and customs.
🔗 Indian Alternatives
| 💊 Product Name | 🏭 Manufacturer | 📝 Description |
|---|---|---|
| Isoxsuprine 10 mg | Healing Pharma | Generic immediate-release isoxsuprine for uterine relaxation |
| Tocolip 10 mg | Cipla Ltd | Standard tablet formulation used in tocolysis |
| Dytarel 10 mg | Sun Pharma | Widely used isoxsuprine immediate-release for preterm labor prevention |
| Isoxsuprine SR 20 mg | Indian Generic Brand | Lower-dose sustained-release option for steady uterine relaxation |
| Vasodilan 10 mg | Multiple Manufacturers | Branded immediate-release version of isoxsuprine, same active ingredient |
📚 References & External Resources
- Drugs.com – Isoxsuprine HCl monograph
- PubMed – Role of beta‑agonists in preterm labor management
- NHS – Advice on preventing premature birth
- World Health Organization – Preterm Birth Fact Sheet
🩺 Expert Commentary – Dr. Rekha Sharma, MD
“Extended-release isoxsuprine capsules like Duvadilan Retards offer longer-lasting uterine relaxation with fewer doses—ideal for managing tocolysis in high‑risk pregnancies.”
⚠️ Disclaimer
This article is for educational purposes only. Duvadilan Retards 40 mg (Isoxsuprine SR) should be used under strict medical supervision. Consult your doctor before use.




