Name: Flucort C
SKU: 23461
Availability: InStock

✅ Active Ingredient Overview Table:

🔬 Active Ingredients:	Fluocinolone Acetonide 0.025% w/w, Ciclopirox Olamine 1% w/w
💊 Indication:	Infected Inflammatory Dermatoses (Eczema, Dermatitis with Secondary Fungal Infection)
🇺🇸 US Brand Equivalent:	No exact combination; topical Fluocinolone (e.g., Synalar) and Ciclopirox (e.g., Loprox) separately
🏭 Manufacturer:	Glenmark Pharmaceuticals Ltd (Founded: 1977)
📦 Packaging:	20 g Tube
🧪 Strength:	Fluocinolone 0.025%, Ciclopirox Olamine 1%
🚚 Delivery Time:	6–15 days

🌿 What is Flucort C Cream 0.025%/1%?

Flucort C Cream combines Fluocinolone Acetonide, a low-to-mid potency corticosteroid, with Ciclopirox Olamine, a broad-spectrum antifungal. The formulation is designed to treat inflammatory dermatoses complicated by fungal colonization or infection. Fluocinolone reduces inflammation, itching, and erythema by modulating cytokine production and vasoconstriction, while Ciclopirox inhibits fungal cell membrane synthesis by chelating iron and disrupting fungal enzymes, effectively eradicating dermatophytes and Candida species. This synergy provides rapid symptomatic relief and addresses underlying infection.

🧬 Pharmacology & Mechanism of Action

Component	Mechanism
Fluocinolone Acetonide 0.025%	• Binds glucocorticoid receptors → downregulates pro-inflammatory mediators (IL-1, TNF-α) → reduces erythema, pruritus, and edema. • Vasoconstrictive effect diminishes redness and heat.
Ciclopirox Olamine 1%	• Chelates polyvalent cations (Fe2+, Al3+) → inhibits metal-dependent enzymes in fungi → disrupts mitochondrial membrane potential → fungicidal/fungistatic activity.
Cream Base	• Emollient water-in-oil base → improves skin hydration, enhances drug penetration, and provides a non-greasy feel to improve compliance.

💡 Indications & Application Guidelines

Condition	Application Regimen
Eczematous Dermatitis with Fungal Superinfection	• Cleanse and gently pat dry affected area. • Apply a thin layer of Flucort C Cream to lesions and 1 cm surrounding margin twice daily (morning & evening). • Duration: Use up to 2 weeks or until infection resolves; discontinue Fluocinolone if prolonged.
Tinea with Inflammation (e.g., Tinea Corporis, Intertrigo)	• Clean area; apply cream twice daily for 2–4 weeks based on fungal clearance. • After 2 weeks, reassess; if inflammation resolved but infection persists, switch to Ciclopirox monotherapy.
Infected Psoriatic/Eczematous Lesions	• Apply cream to infected inflammatory plaques twice daily. • Use for 7–14 days; taper Fluocinolone as inflammation diminishes, continue Ciclopirox for total of 4 weeks to prevent recurrence.

Preparation: Ensure the skin is clean and dry. Avoid occlusive dressings unless specifically directed.
Application: Squeeze sufficient cream; spread evenly over lesion and adjacent skin. Wash hands after application.
Frequency: Twice daily, spacing doses by approximately 12 hours.
Precautions: Avoid contact with eyes and mucous membranes; if accidental, rinse with water. Discontinue if severe irritation or hypersensitivity occurs.

⚠️ Warnings & Side Effects

Common (Local):

Transient burning or stinging at application site
Mild skin drying or peeling
Erythema or slight scaling

Less Common:

Skin atrophy or thinning with extended corticosteroid use
Rosacea-like dermatitis with prolonged application
Contact dermatitis (allergic) to Ciclopirox or excipients

Serious (Rare):

Systemic absorption leading to HPA axis suppression if used on large areas or under occlusion
Secondary bacterial infections due to skin barrier disruption

Precautions:

Hypersensitivity: Contraindicated in patients allergic to Fluocinolone, Ciclopirox, or any cream components.
Pediatric Use: Safety in children under 2 years not established; use under specialist supervision.
Pregnancy & Lactation: Use only if potential benefit outweighs risk; minimal systemic absorption reduces risk but monitor.
Occlusion: Avoid occlusive dressings unless under dermatologic guidance to reduce risk of systemic effects.
Monitoring: If treating extensive areas (>20% BSA) or long-term use (>2 weeks), monitor for signs of systemic corticosteroid absorption (Cushingoid features, growth retardation in children).

🏥 Storage Instructions

Store Flucort C Cream at 20–25°C (68°F–77°F) in original tube. Protect from excessive heat and direct sunlight. Ensure cap is tightly closed after each use. Discard 3 months after opening. Keep out of reach of children.

🌐 Availability & Purchasing

United States: No direct combination product; Fluocinolone and Ciclopirox are available separately by prescription.
United Kingdom & EU: Prescription required; combination topical therapies exist under specialist guidance.
Australia: Prescription necessary; import permitted under TGA guidelines with valid prescription.

Importing from India:
Purchasing Flucort C Cream from India may reduce costs. Ensure compliance with local personal import regulations, maintain a valid prescription, and verify product authenticity to avoid customs delays.

🔗 Authoritative Resources

🔗 Related Topical Therapies (Indian Brands)

Betnovate N Cream – Betamethasone/Neomycin for infected eczematous dermatoses by GSK India.
Fucidin H Cream – Fusidic Acid/Hydrocortisone for infected eczema by Sun Pharma.
Candid B Lotion – Clotrimazole/Beclometasone for inflammatory fungal dermatoses by Glenmark India.

🎥 Educational Video on Combination Anti-Inflammatory and Antifungal Therapy

👩‍⚕️ Expert Insight: Dr. Meera Joshi, Dermatologist

“Flucort C Cream offers comprehensive management for infected inflammatory dermatoses by addressing both the inflammatory cascade and fungal overgrowth. Ensure shorter corticosteroid courses and monitor for resolution of infection before tapering the steroid component.”