Name: Fucibet Cream
SKU: 23291
Availability: InStock

✅ Active Ingredient Overview Table:

🔬 Active Ingredients:	Fusidic Acid 2% w/w, Betamethasone Valerate 0.1% w/w
💊 Indication:	Infected Eczema, Impetiginized Dermatitis, Inflammatory Skin Diseases with Secondary Infection
🇺🇸 US Brand Equivalent:	Comparable Components: Fucidin (Fusidic Acid), Diprolene (Betamethasone Dipropionate)
🏭 Manufacturer:	Sun Pharmaceutical Industries Ltd (Founded: 1983)
📦 Packaging:	15 g Tube
🚚 Delivery Time:	6–15 days

🌿 What is Fucibet Cream?

Fucibet Cream combines Fusidic Acid, a potent topical antibiotic effective against Gram-positive bacteria (including Staphylococcus aureus), with Betamethasone Valerate, a potent topical corticosteroid. This dual-action formulation is indicated for inflammatory dermatoses complicated by bacterial infection—such as infected eczema, impetiginized psoriasis, and weeping dermatitis. Fusidic Acid eradicates pathogenic bacteria, while Betamethasone suppresses inflammation, reducing erythema, itching, and edema for rapid symptomatic relief.

🧬 Pharmacology & Mechanism of Action

Component	Mechanism
Fusidic Acid 2%	• Inhibits bacterial protein synthesis by preventing elongation factor G (EF-G) turnover → bacteriostatic / bactericidal against Gram-positive cocci
Betamethasone Valerate 0.1%	• Binds glucocorticoid receptors → downregulates pro-inflammatory cytokines (IL‑1, TNF‑α) • Inhibits leukocyte migration and mediators → reduces pruritus and erythema
Cream Vehicle	• Semi-occlusive emollient base → enhances penetration of active ingredients, maintains moist environment for healing

💡 Indications & Application Guidelines

Condition	Application Regimen
Infected Eczema / Impetiginized Dermatitis	• Cleanse and gently pat dry affected area. • Apply a thin layer of Fucibet Cream twice daily (morning and evening) to lesions. • Continue for 7–10 days or until infection and inflammation resolve. After improvement, switch to corticosteroid alone if needed.
Infected Psoriatic Lesions	• Cleanse area; apply thin film twice daily for 7 days. • Discontinue Fusidic Acid component after bacterial clearance; continue Betamethasone monotherapy if inflammation persists (max 14 days total).
Impetigo / Secondary Bacterial Infection	• Apply cream twice daily for 5–7 days. • If lesions worsen or fail to improve in 5 days, consider systemic antibiotics per culture results.

Preparation: Wash hands and affected site with mild soap; pat dry.
Application: Dispense pea-sized amount onto fingertip; spread evenly covering entire lesion and a 1-cm margin.
Frequency: Twice daily. If irritation occurs, reduce to once daily.
Precautions: Avoid occlusive dressings unless prescribed. Do not apply to face, groin, or axilla without supervision. Discontinue if hypersensitivity develops.

⚠️ Warnings & Side Effects

Common:

Burning or stinging upon application
Mild dryness or peeling

Less Common:

Contact dermatitis (allergic)
Hypopigmentation with prolonged use of corticosteroid

Serious (Rare):

Secondary fungal overgrowth (e.g., Candida) if used beyond recommended duration
HPA axis suppression (extensive or occluded use of betamethasone)
Development of antibiotic resistance if Fusidic Acid used inappropriately

Precautions:

Limit Betamethasone use to 14 days on body; 7 days in intertriginous areas.
Use Fusidic Acid component for max 10 days to reduce resistance.
Avoid use in children under 2 years without dermatologist oversight.
Monitor for signs of persistent infection; treat accordingly.
Discontinue if hypersensitivity (rash, swelling, severe itching) occurs.

🏥 Storage Instructions

Store Fucibet Cream at 20–25°C (68–77°F) in its original tube. Protect from direct sunlight, heat, and moisture. Ensure cap is tightly closed after each use. Discard 6 months after opening. Keep out of reach of children.

🌐 Availability & Purchasing

United States: Components available separately by prescription (e.g., Fucidin Cream, Betamethasone Valerate). Combination compounding possible in specialized pharmacies.
United Kingdom & EU: Prescription required; similar combination products exist. Dermatologists prescribe for infected dermatoses.
Australia: Prescription-only under PBS; combination products available by specialist prescription.

Importing Fucibet Cream from India can reduce costs. Ensure compliance with local personal importation regulations and maintain valid prescription to avoid customs issues.

🔗 Authoritative Resources

FDA: Topical Antibiotics Overview

🔗 Topical Therapies (Indian Brands)

Betnovate N Ointment – Betamethasone + Neomycin for infected dermatitis.
Betnovate C Cream – Betamethasone + Clioquinol for mixed infections.

🎥 Educational Video on Combination Antibiotic/Steroid Therapy

👨‍⚕️ Expert Insight: Dr. Sangeeta Patel, Dermatologist

“Fucibet Cream offers a synergistic approach for infected eczematous conditions by combining Fusidic Acid’s rapid bactericidal action with Betamethasone’s potent anti-inflammatory effect. Short-course use minimizes resistance and systemic effects.”