Indocap SR 75mg

🌿 What is Indomethacin SR 75 mg (Indocap SR)?

Indocap SR delivers Indomethacin in a sustained-release formulation, providing consistent therapeutic levels over 12–24 hours. Indomethacin is a potent nonsteroidal anti-inflammatory drug (NSAID) that non-selectively inhibits COX-1 and COX-2 enzymes, reducing prostaglandin synthesis and thus alleviating pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, gout, and ankylosing spondylitis.

Clinical studies show that SR formulations improve gastrointestinal tolerability and allow once-daily dosing, enhancing adherence and reducing peak-related adverse effects. Patients report significant reduction in joint pain and flare frequency within the first week of therapy.

For detailed prescribing information and safety warnings, refer to the FDA label for Indocin SR and the Drugs.com monograph. Additional guidance is available from the NHS Medicines A–Z and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Indomethacin’s anti-inflammatory effect arises from blocking both COX isoforms, leading to decreased pain, swelling, and stiffness.

💡 Indications & Dosage

Swallow SR capsules whole; do not crush or chew. Take after food to minimize GI irritation.

⚠️ Warnings & Side Effects

Common:

• Dyspepsia, nausea
• Headache, dizziness
• Edema

Serious (rare):

• GI bleeding or ulceration
• Renal impairment
• Cardiovascular risk (hypertension, thrombotic events)

Use lowest effective dose for shortest duration. Monitor renal function, blood pressure, and GI symptoms periodically.

🏥 Storage Instructions

Store at 20–25°C in original packaging to protect from moisture. Keep out of reach of children.

🌐 Global Availability & Purchasing

• USA: Prescription-only (Indocin SR). Branded and generic SR formulations.
• UK & EU: Prescription required; Indomethacin SR generics available.
• Australia: Prescription and TGA approval for import.

Importing from India can reduce costs; ensure regulatory compliance and valid prescription.

🔗 Related NSAID Therapies

• Diclofenac SR 75 mg – extended-release NSAID.
• Naproxen SR 750 mg – sustained-release naproxen.
• Celecoxib 100/200 mg – COX-2 selective inhibitor.
• Meloxicam 15 mg – preferential COX-2 inhibitor.
• Ibuprofen 400 mg – common NSAID.

🎥 Educational Video on Indomethacin

👩‍⚕️ Expert Insight: Dr. Anjali Verma, Rheumatologist

“Indomethacin SR is a valuable option for chronic inflammatory conditions due to its potent anti-inflammatory properties and once-daily dosing, which improves adherence and reduces GI side effects.”