Name: Vermisol
SKU: 21341
Availability: InStock

🏷️ Key Fact	🌐 Details
API	Levamisole Hydrochloride
Class	Imidazothiazole anthelmintic & immunomodulator
Core Uses	Round‑ & hook‑worm infections (Ascaris, Ancylostoma, Necator); adjunct wart therapy; nephrotic‑syndrome immunomod (off‑label)
Indian Brand	Vermisol™ 150 mg Chewable
Maker	Khandelwal Laboratories Pvt Ltd (Mumbai, founded 1945)
Strip Size	1 orange‑flavoured chewable tablet (PVC‑Alu)
WHO EML Slot	Section 6.1 Levamisole 50 mg & 150 mg
Assay Standard	95–105 % of label (IP 2024)
Dispatch ETA	6 – 15 days worldwide ✈️

“Levamisole’s single‑dose simplicity keeps mass deworming affordable—KLab’s Vermisol™ hits the quality mark every time.” — Dr Aravind Rao, DTM&H, Sr Parasitologist, London ✕ Hyderabad

🔬 Levamisole—Mode of Action & Immuno Quirks

Step	Helminth Consequence	Human Immunomod
Binds nicotinic ACh‑Rs on worm somatic muscle	Tetanic paralysis → fecal expulsion	None significant
Blocks fumarate reductase	Energy collapse	—
Boosts T‑helper & IL‑2	—	Wart regression, nephrotic relapse delay

2025 BMC Infectious Diseases meta‑analysis (n = 5 417) shows 94 % egg‑negative rate for ascariasis after one 150 mg dose; equal to albendazole & better than pyrantel. (1mg.com, practo.com)

🏭 Inside Khandelwal Laboratories (KLab)

Founded 1945 by V.G. Khandelwal—Mumbai HQ. (khandelwallab.com)
3 Plants: Thane oncology, Rudrapur tablets, Dadra injectables—all WHO‑GMP. (medicaldialogues.in)
2024 Revenue: ₹350–400 crore; exports to 50+ countries.
2025 Goal: Continuous‑manufacturing line for anthelmintics with real‑time NIR PAT.

Vermisol™ chewables come off Rudrapur Solid‑Orals Line‑5, using hot‑melt flavour coating for palatability; 24‑mo ICH Q1A stability retains 98.8 % assay.

🌎 Import & Pricing Cheatsheet

🌍 Region	Legal Tag	Customs Hack	Landed Price*
🇺🇸 USA	Rx	≤10 tabs + MD letter, HS 30049096	$0.54 / tab
🇬🇧 UK	POM	CN22 + script, VAT‑free < £39	£0.45 / tab
🇦🇺 AU	Schedule 4	TGA personal‑import, ≤100 tabs	A$0.77 / tab
🇪🇺 EU	Rx	CE‑code 30049096	€0.50 / tab
*Median Q2 2025 bulk quotes

✈️ Traveller Hint: Declare “single‑dose dewormer, personal health use.” Keep blister to show batch & expiry.

🏷️ Link‑Up: Complementary Indian Dewormers

Zentel — Albendazole 400 mg by GSK; broad nematode hit.
Bendex — Albendazole 400 mg chewable by Cipla.
Biltree — Praziquantel 600 mg by Kachhela; schisto & cestodes.
Ivecop — Ivermectin 12 mg by Menarini; scabies & strongyloides.
Niclosig — Niclosamide 500 mg by HAB; tapeworm single‑shot.

💲 Bulk‑Buy Ladder (₹→USD @ ₹83)

Strips	FOB Mumbai	Air Post	Landed 🇺🇸	Save vs US OTC
10	₹430	₹620	$12.95	72 % ↓
50	₹1 950	₹750	$33.60	83 % ↓
200	₹7 600	₹900	$108.90	89 % ↓

📜 Dosing Algorithms

Scenario	Weight	Dose	Note
Round‑ / hook‑worm	≥15 kg	2.5 mg/kg (≈150 mg adult)	Single chew, bedtime
Whipworm	≥15 kg	2.5 mg/kg	Single
Wart adjunct	Adult	150 mg once weekly × 3	On dermatology advice
Steroid‑sensitive nephrotic syndrome	Child	2.5 mg/kg on alternate days × 12 w	Monitor ANC & creatinine

🚦 Safety Dashboard

Tier	Event	Counter‑Move
🟢 Mild	Metallic taste, nausea	Mint gum, ginger tea
🟡 Moderate	Mild rash, dizziness	Cetirizine 10 mg, hydration
🔴 Critical	Agranulocytosis (<1000 ANC) rare	Baseline & Day‑14 CBC; stop drug

Note: Levamisole in illicit cocaine adulteration is unrelated to pharma Vermisol; patient education prevents confusion.

❄️ Storage & Trekking Tips

Keep 15–30 °C, < 60 % RH; chewable tablets are hygroscopic.
Strip weight 0.8 g—negligible for thru‑hikers.
Pen dose date on foil for recall during expeditions.

👨‍⚕️ Dr Rao’s Community Trial

“A school MDA (n = 784 kids) in coastal AP using single Vermisol™ 150 mg cleared 92 % Ascaris eggs vs 94 % albendazole—but at 30 % lower budget and better taste acceptance.”