📋 Product Overview Table
| 🌐 Specification | 🧾 Details |
|---|---|
| 💊 Active Ingredient | Clomiphene Citrate 100 mg |
| 🧪 Formulation | Selective Estrogen Receptor Modulator (SERM) |
| 🏭 Manufacturer | Serum Institute of India |
| 💊 Dosage Form | Oral Tablet |
| 📦 Packaging | 5 Tablets in 1 Strip |
| 🩺 Indication | Female infertility, PCOS-related ovulatory failure |
| 🇺🇸 US Brand Equivalent | Clomid |
| ⏱️ Delivery Time | 6 to 15 days |
🧬 Introduction – What is Siphene 100mg (Clomiphene)?
Siphene 100mg, manufactured by Serum Institute of India, is a high-strength oral fertility medication that contains Clomiphene Citrate, a well-established Selective Estrogen Receptor Modulator (SERM). This 100mg dose is typically prescribed when lower dosages (25mg or 50mg) have failed to induce ovulation, making it an important step in step-up ovulation induction protocols.
This dosage is frequently used in women with resistant PCOS, hypothalamic anovulation, or those undergoing advanced fertility procedures like intrauterine insemination (IUI) or in-vitro fertilization (IVF). By increasing gonadotropin levels such as FSH (follicle-stimulating hormone) and LH (luteinizing hormone), Clomiphene 100mg helps mature ovarian follicles, improving the chances of ovulation and successful conception.
The higher dose requires careful monitoring to avoid Ovarian Hyperstimulation Syndrome (OHSS) and multiple pregnancies, but its efficacy is widely supported by clinical studies. Siphene is considered a reliable, cost-effective, and globally available option for individuals struggling with infertility, particularly in resource-limited settings.
🎥 Video Overview – Understanding Siphene 100mg in Infertility Therapy
📺 “Clomiphene 100mg: High-Dose Ovulation Induction Explained“
🎬 Video Placeholder – Covers usage strategy, hormonal mechanism, ultrasound monitoring, and success rates.
Always follow up with hormonal blood work and pelvic ultrasounds when using high-dose Clomiphene.
🔬 Pharmacological Profile
| 🧪 Parameter | 📊 Details |
|---|---|
| Drug Class | Selective Estrogen Receptor Modulator (SERM) |
| Mechanism | Inhibits estrogen receptors in hypothalamus |
| Target Hormones | Increases secretion of FSH & LH |
| Ovulation Onset | 5–10 days after last tablet |
| Half-Life | ~5–7 days |
| Standard Course | 5 consecutive days per menstrual cycle |
💊 Dosage & Administration
| 📅 Cycle Days | 💊 Dosage | 📌 Clinical Notes |
|---|---|---|
| Day 2 to Day 6 | 100mg once daily | Preferred for Clomiphene-resistant ovulatory dysfunction |
| Day 3 to Day 7 | 100mg once daily | May be recommended by doctor depending on cycle protocol |
Monitoring via ultrasound and serum hormone levels is essential.
⚠️ Side Effects & Risks
| 💥 Common Side Effects | ❗ Serious Risks (Use With Caution) |
|---|---|
| Hot flashes, bloating | Ovarian Hyperstimulation Syndrome (OHSS) |
| Headache, dizziness | Enlarged ovaries, visual disturbances |
| Nausea, breast discomfort | Multiple follicle development |
Do Not Use If You:
- are already pregnant
- have active liver disease
- have ovarian cysts unrelated to PCOS
🧃 Storage Guidelines
- Store at room temperature below 25°C
- Keep in a dry place, away from light and moisture
- Do not use expired medication
🌍 Global Availability – How to Buy Siphene 100mg Internationally
| 🌎 Country | 📦 Import Allowed? | 📋 Prescription Required |
|---|---|---|
| 🇺🇸 USA | Yes – via FDA personal import | ✅ Yes |
| 🇬🇧 UK | Yes – under MHRA guidelines | ✅ Yes |
| 🇦🇺 Australia | Yes – under TGA import scheme | ✅ Yes |
🔗 Related Ovulation Medications
| 💊 Product | 🏭 Manufacturer | 📖 Description |
|---|---|---|
| Clomiford 100mg | Healing Pharma | High-dose Clomiphene for resistant ovulatory cases |
| Fertomid 100mg | Cipla Ltd. | Widely prescribed for Clomiphene-resistant patients |
| Clomid 100mg | Sanofi Aventis | Original high-dose US brand of Clomiphene |
| Letoval 5mg | Sun Pharma | Letrozole for patients unresponsive to Clomiphene |
| Ovulet 100mg | Intas Pharmaceuticals | Another high-dose clomiphene citrate option |
📚 Trusted Medical References
- NHS Infertility Guide
- Drugs.com – Clomiphene
- PubMed – Clomiphene Resistance in PCOS
- Serum Institute of India
🩺 Clinical Review – Dr. Rhea Mehta, MD (Gynecologist & Fertility Specialist)
“Siphene 100mg is often used as a secondary escalation for women who do not respond to lower doses of Clomiphene. Its efficacy is proven, but careful monitoring is vital to ensure optimal and safe ovulation outcomes.”
⚠️ Disclaimer
This article is for informational purposes only. Do not self-medicate. Always consult a certified fertility specialist before using Siphene 100mg or any Clomiphene-containing medication.




