โ Active Ingredient Overview Table:
| ๐ฌ Active Ingredient (Generic Name): | Nicotine |
|---|---|
| ๐ Indication: | Smoking Cessation (Nicotine Replacement Therapy) |
| ๐บ๐ธ US Brand: | Nicorette, Thrive |
| ๐ญ Manufacturer: | Cipla Limited (Founded: 1935) |
| ๐ฆ Packaging: | 9 Chewing Gums per Packet |
| ๐งช Strength: | 2 mg |
| ๐ Delivery Time: | 6โ15 days |
๐ฟ What is Nicotex 2 mg Nicotine Gum?
Nicotex 2 mg provides a controlled dose of nicotine via chewing gum, serving as a first-line nicotine replacement therapy (NRT). It helps smokers manage withdrawal symptomsโcravings, irritability, difficulty concentratingโby delivering nicotine through the buccal mucosa, thereby reducing the urge to smoke.
Clinical studies indicate that 2 mg gum is ideal for lighter smokers (fewer than 20 cigarettes per day) or those who experience mild to moderate nicotine cravings. Users chew the gum until a tingling sensation appears, then park it between cheek and gum to allow gradual nicotine release over 20โ30 minutes. This method achieves peak nicotine levels within 30 minutes, alleviating withdrawal without the harmful constituents of tobacco smoke.
๐งฌ Pharmacology & Mechanism of Action
| Attribute | Detail |
|---|---|
| Chemical Formula | C10H14N2 |
| Molecular Weight | 162.23 g/mol |
| Bioavailability | ~50โ60% (buccal absorption) |
| Metabolism | Hepatic (CYP2A6) |
| Half-Life | ~2 hours |
Nicotine activates nicotinic acetylcholine receptors, releasing dopamine in reward pathways to reduce craving and withdrawal symptoms.
๐ก Indications & Dosing Guidelines
| Smoking Category | Dosing |
|---|---|
| Light Smokers (<20/day) | 1 gum every 1โ2 hours as needed (max 15 gums/day) |
| Intense Cravings | Up to 2 gums every 1โ2 hours |
Chew slowly until tingling, then park; resume chewing when tingle dissipates. Use for up to 12 weeks, tapering over final 4 weeks.
โ ๏ธ Warnings & Side Effects
Common:
- Oral irritation, hiccups
- Dyspepsia, jaw ache
Serious (rare):
- Arrhythmias in patients with cardiovascular disease
- Hypersensitivity reactions
Use caution in patients with TMJ disorder or significant cardiovascular disease. Advise proper chewing technique to minimize side effects.
๐ฅ Storage Instructions
Store Nicotex gum at 20โ25ยฐC in a dry place. Keep sealed in foil packet to preserve freshness. Keep out of reach of children.
๐ Availability & Purchasing
- USA: OTC (Nicorette); Ciplaโs Nicotex imported by prescription.
- UK & EU: OTC availability; generic nicotine gums common.
- Australia: OTC; follow TGA guidelines.
Importing from India can reduce costs; ensure you comply with local regulations.
๐ Related Nicotine Replacement Products
- Nicotex 4 mg Gum โ lower-strength gum.
๐ฅ Educational Video on Nicotine Replacement Therapy
๐ฉโโ๏ธ Expert Insight: Dr. Rajeev Mehta, Pulmonologist
โNicotex 2 mg gum is effective for mild-to-moderate smokers. Proper chewing technique and combination with behavioral support significantly improve quit rates.โ




