✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Mupirocin
💊 Indication:	Impetigo, Infected Minor Skin Lesions (Furuncles, Folliculitis)
🇺🇸 US Brand Equivalent:	Bactroban
🏭 Manufacturer:	Wallace Pharmaceuticals Pvt. Ltd. (Founded: 1977)
📦 Packaging:	10 g Tube
🧪 Strength:	2 % w/w
🚚 Delivery Time:	6 – 15 days

🌿 What Is Mupirocin 2 % (B-Bact Ointment)?

Topical antibiotics are integral to managing localized skin infections because they achieve high tissue concentrations with minimal systemic absorption. B-Bact Ointment delivers 2 % mupirocin, a unique antibacterial agent that selectively inhibits bacterial isoleucyl-tRNA synthetase, halting protein synthesis in susceptible Gram-positive organisms—particularly Staphylococcus aureus and Streptococcus pyogenes.

In impetigo—characterized by honey-colored crusts around the nose and mouth—B-Bact Ointment eradicates superficial lesions, limits spread, and accelerates healing. Similarly, infected minor wounds (e.g., furuncles, folliculitis, small traumatic abrasions) respond quickly to topical mupirocin, reducing the need for systemic antibiotics. The semi-occlusive petrolatum base in B-Bact creates a moist environment, promoting wound healing and reducing scarring.

For additional clinical guidance, refer to the FDA Mupirocin Label and the Drugs.com Mupirocin Monograph. Further details on impetigo management are available at the NHS Impetigo Overview and the WHO Essential Medicines List.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C17H26N2O9S2
Molecular Weight	500.6 g/mol
Mode of Action	Inhibits bacterial isoleucyl-tRNA synthetase → halts protein synthesis
Spectrum of Activity	Primarily Gram-positive cocci (including MRSA), some Gram-negative bacteria
Resistance Risk	Low when used appropriately; resistance may emerge with prolonged or off-label use

Mupirocin’s mechanism of action is distinct from other topical antibiotics, reducing cross-resistance. Though primarily used topically, intranasal mupirocin has off-label utility in eradicating nasal MRSA colonization under clinical supervision.

💡 Indications & Application Guidelines

Condition	Application Regimen
Impetigo (Non-bullous & Bullous)	Cleanse area → Apply B-Bact thinly 2–3 times daily for 5–7 days
Infected Minor Wounds (Furuncles, Folliculitis)	Cleanse → Apply ointment twice daily until resolution (typically 3–5 days)
Nasal MRSA Eradication (Off-Label)**	Apply a small amount inside each nostril twice daily for 5 days (in healthcare settings)

Preparation: Gently cleanse the lesion with mild soap and water, pat dry with a sterile gauze.
Application: Squeeze a pea-sized portion onto a sterile cotton swab or gloved fingertip; apply a thin layer to the entire affected area.
Frequency: Impetigo usually requires 2 – 3 applications per day; minor skin infections often resolve after 3 – 5 days of twice-daily use.
Nasal Use: Wrap a gloved fingertip in sterile gauze or use a swab to distribute a small amount of ointment in each nostril, ensuring coverage of anterior nares.

Do not occlude unless directed; avoid eye contact. If accidental contact occurs, rinse thoroughly with water. For nasal application, do not ingest; use only under healthcare supervision.

⚠️ Warnings & Side Effects

Common (≤ 10 %):

Local irritation (burning, stinging, itching)
Dryness or mild erythema at the application site

Serious (Rare):

Secondary fungal infection (e.g., Candida overgrowth)
Hypersensitivity reactions (rash, urticaria, anaphylaxis)
Systemic toxicity if applied to large areas or open wounds
Discontinue B-Bact if severe local irritation or signs of hypersensitivity develop.
Avoid ingestion and eye contact; seek immediate care if ocular exposure occurs.
Do not use on deep or puncture wounds, animal bites, or serious burns without medical prescription.

🏥 Storage Instructions

Store B-Bact Ointment at 20 °C – 25 °C (68 °F – 77 °F) in its original tube. Protect from light and moisture. Keep out of reach of children and pets.

🌐 Availability & Purchasing

United States: Bactroban (Mupirocin) is prescription-only. Generic mupirocin ointment may be available through compounding pharmacies.
United Kingdom: Prescription required; mupirocin topical preparations are widely accessible.
Australia: Schedule 4 (Prescription-only); mupirocin mostly used for impetigo and skin infections.

Patients in these regions may import B-Bact from India under personal importation regulations if a valid prescription is provided. Ensure compliance with customs and local laws to avoid delays.

🔗 Internal Links to Authoritative Resources

🔗 Related Dermatology Products (Indian Brands)

Clindac A Gel – Clindamycin Phosphate 1 % gel for inflammatory acne.
Adapen Gel – Adapalene 0.1 % gel for comedonal and inflammatory acne.
Aziderm 10 % Gel – Azelaic Acid 10 % gel for acne and rosacea.

🎥 Educational Video on Mupirocin & Topical Antibiotics

👨‍⚕️ Expert Insight: Dr. Priya Kapoor, Dermatologist

“Topical mupirocin ointment is first-line for superficial skin infections like impetigo. Early, targeted therapy shortens lesion duration, curbs transmission, and often obviates the need for oral antibiotics—especially important in pediatric populations.”

Note: Consult a healthcare professional before using B-Bact Ointment. Always follow local prescribing guidelines and maintain hygiene to prevent reinfection.