💊 Natrise 30 mg (Tolvaptan) — by Sun Pharma

Advanced therapy for hyponatremia & polycystic kidney disease • Global availability via BuyAllMD

🧾 Product Overview

Brand Name	Natrise 30 mg
Generic Name (Active Ingredient)	Tolvaptan
Strength	30 mg
Dosage Form	Tablet (Oral use)
Manufacturer	Sun Pharmaceutical Industries Ltd (India)
Packaging	4 tablets in 1 strip (blister pack)
Therapeutic Class	Vasopressin V2-Receptor Antagonist
Estimated Delivery	Australia 6–12 days • US/UK/EU 8–18 days

🧬 About Natrise 30 mg

Natrise 30 mg contains Tolvaptan, a selective vasopressin V2-receptor antagonist formulated by Sun Pharma.
It is prescribed for the management of hyponatremia associated with congestive heart failure, liver cirrhosis, or SIADH, and for autosomal dominant polycystic kidney disease (ADPKD) to reduce cyst progression and maintain kidney health.
The 30 mg strength allows flexible titration for patients requiring higher aquaretic response.

⚗️ Mechanism of Action

Tolvaptan competitively blocks vasopressin V2 receptors in the renal collecting ducts, leading to increased free-water excretion (aquaretic effect) without disturbing electrolyte balance.
This controlled diuresis corrects sodium levels and reduces fluid overload, improving symptoms of edema and congestion.
In ADPKD, it limits cyst growth by reducing intracellular cAMP accumulation.

💊 Dosage & Administration

Indication	Recommended Dose	Frequency	Remarks
Hyponatremia / SIADH / CHF	Start at 15 mg, may increase to 30 mg daily	Once daily	Monitor serum sodium and hydration
ADPKD	45 mg AM / 15 mg PM (gradually to 90 mg total)	Split dose	Requires liver-function monitoring

⚠️ Side Effects & Warnings

Thirst and frequent urination (polyuria)
Dry mouth and fatigue
Potential increase in liver enzymes — regular LFT check required
Contraindicated in anuria and patients unable to perceive thirst

🌍 Global Shipping & Availability

Region	Availability	Delivery Time
Australia	Priority stock	6–12 days
USA	Available	8–18 days
UK / EU	Available	10–20 days

🔗 Related Indian Alternatives

Brand	Active Ingredient	Manufacturer	Link
Tolvact 30 mg	Tolvaptan	Cipla Ltd	View
Tolvase 30 mg	Tolvaptan	Zydus Lifesciences	View

📚 External References

👨‍⚕️ Doctor’s Expert Opinion

“For patients with resistant hyponatremia or progressive ADPKD, Tolvaptan 30 mg provides an effective step-up therapy to achieve sustained electrolyte correction and slower renal volume increase.” — Dr. K. Rao, Nephrologist

🩺 Medical Disclaimer

This content is for educational purposes only. Tolvaptan should be used under medical guidance due to potential liver effects and electrolyte changes.
BuyAllMD offers verified Sun Pharma products with global delivery — consult a healthcare professional before use.