Name: Permite
SKU: 23076
Availability: InStock

✅ Active Ingredient Overview Table:

🔬 Active Ingredient (Generic Name):	Permethrin
💊 Indication:	Scabies (Sarcoptes scabiei infestation)
🇺🇸 US Brand:	Elimite, Nix
🏭 Manufacturer:	Curatio Healthcare India Pvt Ltd (Founded: 2005)
📦 Packaging:	60 g Tube
🧪 Strength:	5% w/w
🚚 Delivery Time:	6–15 days

🌿 What is Permethrin 5% Cream (Permite)?

Permite Cream offers a robust single-dose scabicide, containing 5% permethrin designed to eliminate Sarcoptes scabiei mites and eggs in one application. Scabies causes severe itching, rash, and secondary infections; Permite penetrates the stratum corneum, binding mites’ sodium channels to induce rapid paralysis and death. Its extended persistence in skin layers ensures comprehensive eradication, reducing the need for repeated treatments.

By applying Permite Cream overnight, patients experience significant symptom relief within days. The 60 g tube provides ample coverage for adults and children, supporting household treatment to prevent reinfestation. Curatio’s formulation balances potency with skin tolerability, making it suitable for diverse patient populations.

🧬 Pharmacology & Mechanism of Action

Attribute	Detail
Chemical Formula	C21H20Cl2O3
Molecular Weight	391.29 g/mol
Mode of Action	Voltage-gated sodium channel disruption
Residual Activity	Up to 24 hours

Permethrin disrupts mite neural function by locking sodium channels open, causing prolonged depolarization and paralysis of all life stages.

💡 Indications & Application Protocol

Condition	Application Steps
Scabies Infestation	• Apply to dry skin from neck to soles.
• Leave on for 8–14 hours (overnight).
• Rinse off thoroughly in the morning.
• Repeat once after 7 days if symptoms persist.

Ensure full-body coverage including under nails and skin folds. Wash linens and clothes in hot water.

⚠️ Warnings & Side Effects

Common:

Mild burning, stinging at application site
Itching, redness due to mite death

Serious (rare):

Allergic contact dermatitis
Neurotoxicity (avoid mucous membranes)

Do not apply to broken or inflamed skin. In case of eye contact, rinse immediately with water. Use with caution in infants under 2 months and pregnant women.

🏥 Storage Instructions

Store Permite Cream at 20–25°C in original tube. Protect from light and moisture. Keep out of reach of children.

🌐 Availability & Purchasing

USA: Prescription-only (Elimite); generic permethrin creams for lice OTC.
UK & EU: Prescription required; permethrin scabicide accessible.
Australia: Prescription and TGA approval required.

Curatio’s Permite Cream offers an economical and effective option. Always follow local prescribing guidelines.

🔗 Related Parasitic Treatments

Permiforce Cream 5% – healing pharma permethrin.

🎥 Educational Video on Scabies Treatment

👨‍⚕️ Expert Insight: Dr. Manish Verma, Dermatologist

“Permethrin 5% remains the cornerstone for scabies management. A single overnight application of Permite Cream typically achieves cure; patient education on household decontamination is essential to prevent reinfestation.”